J Neurol Surg B Skull Base
DOI: 10.1055/s-0044-1792079
Original Article

Anterior Skull Base Reconstruction Using a Vascularized Pericranial Flap: A Promising Alternative in Sinonasal Malignancies

1   Department of Neurological Sciences, Christian Medical College, Vellore, India
,
Arun Govind
2   Unit-1 (Head and Neck Skull Base Surgery), Department of ENT, Christian Medical College, Vellore, India
,
Rajan Sundaresan Vediappan
2   Unit-1 (Head and Neck Skull Base Surgery), Department of ENT, Christian Medical College, Vellore, India
,
2   Unit-1 (Head and Neck Skull Base Surgery), Department of ENT, Christian Medical College, Vellore, India
,
Gandham Edmond Jonathan
1   Department of Neurological Sciences, Christian Medical College, Vellore, India
,
Krishnaprabhu Raju
1   Department of Neurological Sciences, Christian Medical College, Vellore, India
› Author Affiliations

Abstract

Background As the scope of endoscopic techniques continues to evolve in the treatment of advanced sinonasal malignancies, the primary challenge is the reconstruction of the resulting anterior skull base dural defect.

Objective This study aimed to assess the efficacy of vascularized pericranial flap reconstruction in addressing anterior skull base defects in sinonasal malignancies, particularly when alternative reconstructive methods, such as nasoseptal flaps, are not viable.

Methods We conducted a retrospective review of nine patients who underwent endoscopic resection of sinonasal malignancy followed by vascularized pericranial flap. Our analysis aimed to evaluate the surgical methods utilized, identify any complications that occurred, and assess the postoperative results of the patients.

Results Excluding the singular instance of tension pneumocephalus that emerged during the immediate postoperative period, necessitating surgical intervention, our clinical experience was devoid of any complications, with a median follow-up duration of 18 months. It is worth noting that no cases of cerebrospinal fluid leaks or meningitis were reported. Moreover, the follow-up check endoscopy verified the successful integration of the flap and its efficacious coverage of the resection site.

Conclusion This study underscores the benefits of using vascularized pericranial flaps as an alternative solution for anterior skull base reconstruction in sinonasal malignancies. The availability of the pericranial flap in the local region, along with its robust blood supply, and the positive outcomes observed in this preliminary series collectively indicate its potential as an integral component of multi-layered reconstruction techniques for addressing anterior skull base defects.



Publication History

Received: 13 February 2024

Accepted: 06 October 2024

Article published online:
28 October 2024

© 2024. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 
  • References

  • 1 Yavuz HB, Aslıer M, Demir UL, Kasapoğlu F. Endoscopic surgery for sinonasal cancer: Uludağ experience. Eur J Rhinol Allergy 2019; 2: 75-78
  • 2 Lee CH, Hur DG, Roh HJ. et al. Survival rates of sinonasal squamous cell carcinoma with the new AJCC staging system. Arch Otolaryngol Head Neck Surg 2007; 133 (02) 131-134
  • 3 Patel SG, Singh B, Polluri A. et al. Craniofacial surgery for malignant skull base tumors: report of an international collaborative study. Cancer 2003; 98 (06) 1179-1187
  • 4 Wood JW, Eloy JA, Vivero RJ. et al. Efficacy of transnasal endoscopic resection for malignant anterior skull-base tumors. Int Forum Allergy Rhinol 2012; 2 (06) 487-495
  • 5 Snyderman CH, Wang EW, Zenonos GA, Gardner PA. Reconstruction after endoscopic surgery for skull base malignancies. J Neurooncol 2020; 150 (03) 463-468
  • 6 Yoshioka N, Rhoton Jr AL. Vascular anatomy of the anteriorly based pericranial flap. Neurosurgery 2005; 57 (01) 11-16 , discussion 11–16
  • 7 Higgins TS, Thorp B, Rawlings BA, Han JK. Outcome results of endoscopic vs craniofacial resection of sinonasal malignancies: a systematic review and pooled-data analysis. Int Forum Allergy Rhinol 2011; 1 (04) 255-261
  • 8 Hadad G, Bassagasteguy L, Carrau RL. et al. A novel reconstructive technique after endoscopic expanded endonasal approaches: vascular pedicle nasoseptal flap. Laryngoscope 2006; 116 (10) 1882-1886
  • 9 Harvey RJ, Parmar P, Sacks R, Zanation AM. Endoscopic skull base reconstruction of large dural defects: a systematic review of published evidence. Laryngoscope 2012; 122 (02) 452-459
  • 10 Zanation AM, Snyderman CH, Carrau RL, Kassam AB, Gardner PA, Prevedello DM. Minimally invasive endoscopic pericranial flap: a new method for endonasal skull base reconstruction. Laryngoscope 2009; 119 (01) 13-18
  • 11 Patel MR, Shah RN, Snyderman CH. et al. Pericranial flap for endoscopic anterior skull-base reconstruction: clinical outcomes and radioanatomic analysis of preoperative planning. Neurosurgery 2010; 66 (03) 506-512 , discussion 512
  • 12 Santamaría A, Langdon C, López-Chacon M. et al. Radio-anatomical analysis of the pericranial flap “money box approach” for ventral skull base reconstruction. Laryngoscope 2017; 127 (11) 2482-2489
  • 13 Giurintano J, McDermott MW, El-Sayed IH. Vascularized pericranial flap for endonasal anterior skull base reconstruction. J Neurol Surg B Skull Base 2021; 83 (02) 133-136
  • 14 Calvaruso F, Lo Manto A, Bisi N. et al. Pericranial flap-based multilayer reconstruction of endoscopic transcribriform craniectomy for sinonasal malignancies. Laryngoscope 2023; 133 (11) 2942-2947