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J Wrist Surg
DOI: 10.1055/s-0044-1793831
Case Report

Giant Cell Tumor of Capitate with Secondary Aneurysmal Bone Cyst: A Case Report

Suneel Ramanujapuram 
1   Department of Orthopaedic Surgery, Medicover Hospitals, Hyderabad, Telangana India
,
Apurve Parameswaran 
1   Department of Orthopaedic Surgery, Medicover Hospitals, Hyderabad, Telangana India
,
Lakshmi Manasa Perubhotla
2   Department of Pathology, Medicover Hospitals, Hyderabad, Telangana India
,
Murtuza Ahmed Mohammed
1   Department of Orthopaedic Surgery, Medicover Hospitals, Hyderabad, Telangana India
,
Harshil Nitinkumar Shah
1   Department of Orthopaedic Surgery, Medicover Hospitals, Hyderabad, Telangana India
,
Krishna Kiran Eachempati 
1   Department of Orthopaedic Surgery, Medicover Hospitals, Hyderabad, Telangana India
› Author Affiliations Funding The authors declare that no funds, grants, or other support were received for the preparation of this manuscript.
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Abstract

Background Giant cell tumors (GCTs) of the carpal bones are rare. GCTs of the hand tend to be aggressive, could result in multifocal presentation, and have a high rate of recurrence.

Case Description We report a rare case of GCT of the capitate with secondary aneurysmal bone cyst (ABC) in a 40-year-old man. The patient presented with complaints of pain and swelling over his right wrist since 6 months. Radiographs showed the presence of a lytic lesion in the capitate. Magnetic resonance imaging scanning revealed a well-defined, lobulated, multiseptate lytic lesion involving the entire capitate, extending into its subarticular regions. Fine-needle aspiration revealed findings suggestive of a GCT. He underwent en-bloc excision of the capitate, bone grafting of the defect using an appropriately sized bicortical iliac crest autograft, and third carpometacarpal and midcarpal fusion. Histopathological examination of the lesion confirmed the presence of a GCT, with a secondary ABC. At 3 years following surgery, he was asymptomatic with no signs of tumor recurrence, radiocarpal arthritis, or instability. He was able to perform 45 and 60 degrees of wrist extension and flexion, respectively.

Literature Review To our knowledge, there are no prior reported cases of GCT of the capitate with a secondary ABC.

Clinical Relevance GCTs of the hand in general have a high rate of recurrence. The presence of a super-added ABC could further increase this risk. In the authors' opinion, en-bloc excision of the affected bone, reconstruction of the defect, and appropriate fusion is the optimal mode of management of these cases.

Keywords

giant cell tumor - secondary aneurysmal bone cyst - capitate - carpal bone tumor

Informed Consent

Informed consent was obtained from the patient included in the study.




Publication History

Received: 08 July 2024

Accepted: 09 October 2024

Article published online:
08 November 2024

© 2024. Thieme. All rights reserved.

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  • References

  • 1 Angelini A, Mavrogenis AF, Ruggieri P. Giant cell tumor of the capitate. Musculoskelet Surg 2011; 95 (01) 45-48
    CrossrefPubMedGoogle Scholar
  • 2 Narayana Gowda BS, Mohan Kumar J. Giant cell tumor (GCT) of capitate. J Orthop Case Rep 2012; 2 (01) 21-23
    PubMedGoogle Scholar
  • 3 Chalidis BE, Dimitriou CG, Givissis PK. Tricortical bone grafting with limited midcarpal and carpometacarpal fusion for the treatment of giant cell tumor of the capitate. J Wrist Surg 2021; 10 (04) 347-349
    Article in Thieme ConnectPubMedGoogle Scholar
  • 4 Oufkir AA, Lazerges C, Coulet B, Chammas M. Giant cell tumor of the capitate treated with excision and midcarpal fusion. J Wrist Surg 2017; 6 (03) 238-243
    Article in Thieme ConnectPubMedGoogle Scholar
  • 5 Afshar A, Tabrizi A, Aidenlou A, Abbasi A. Giant cell tumor of the capitate bone. J Hand Microsurg 2018; 10 (03) 158-161
    Article in Thieme ConnectPubMedGoogle Scholar
  • 6 Duman S, Sofu H, Camurcu Y, Gursu S, Oke R. Giant cell tumor of the capitate: an unusual case with 10 years follow-up. SICOT J 2015; 1: 18
    CrossrefPubMedGoogle Scholar
  • 7 McDonald DJ, Schajowicz F. Giant cell tumor of the capitate. A case report. Clin Orthop Relat Res 1992; (279) 264-268
    PubMedGoogle Scholar
  • 8 Li M, Gan Y, Shi D, Zhao J. Huge aneurysmal bone cyst secondary to giant cell tumor of the hand phalanx: a case report and related literature. BMC Cancer 2020; 20 (01) 233
    CrossrefPubMedGoogle Scholar
  • 9 Liu H, Liu D, Jiang X. et al. Aneurysmal bone cyst secondary to giant cell tumor of the extremities: a case series of 30 patients. Am J Transl Res 2022; 14 (05) 3198-3206
    PubMedGoogle Scholar
  • 10 Kamal AF, Hilmy F. Giant cell tumor with secondary aneurysmal bone cyst of the left calcaneus. Int J Surg Case Rep 2022; 100: 107697
    CrossrefPubMedGoogle Scholar
  • 11 Tripathy SK, Doki S, Behera G, Sable M. giant cell tumor with secondary aneurysmal bone cyst of the patella: a case report. Cureus 2019; 11 (10) e5819
    PubMedGoogle Scholar
  • 12 Averill RM, Smith RJ, Campbell CJ. Giant-cell tumors of the bones of the hand. J Hand Surg Am 1980; 5 (01) 39-50
    CrossrefPubMedGoogle Scholar
  • 13 Murray PM, Berger RA, Inwards CY. Primary neoplasms of the carpal bones. J Hand Surg Am 1999; 24 (05) 1008-1013
    CrossrefPubMedGoogle Scholar
  • 14 Gupta GG, Lucas GL, Pirela-Cruz M. Multifocal giant cell tumor of the capitate, hamate, and triquetrum: a case report. J Hand Surg Am 1995; 20 (06) 1003-1006
    CrossrefPubMedGoogle Scholar
  • 15 Ansari MT, Prakash P K, Machhindra MV. Wrist preserving surgery for multifocal giant cell tumor of carpal bones in a skeletally immature patient: a case report. Orthop Surg 2014; 6 (04) 322-325
    CrossrefPubMedGoogle Scholar
  • 16 Bokemper MK, Araiza ET, Templeton KJ, Fox TJ. Third-ray and capitate resection with limited midcarpal fusion for recurrent giant cell tumor: a case report. JBJS Case Connect 2018; 8 (01) e15
    CrossrefPubMedGoogle Scholar
  • 17 Athanasian EA, Wold LE, Amadio PC. Giant cell tumors of the bones of the hand. J Hand Surg Am 1997; 22 (01) 91-98
    CrossrefPubMedGoogle Scholar
  • 18 Howard FM, Lassen K. Giant cell tumor of the capitate. J Hand Surg Am 1984; 9 (02) 272-274
    CrossrefPubMedGoogle Scholar
  • 19 Tsukamoto S, Aiba H, Righi A. et al. Giant cell tumor of bone with secondary aneurysmal bone cyst does not have a higher risk of local recurrence. J Surg Oncol 2023; 128 (02) 350-358
    CrossrefPubMedGoogle Scholar
  • 20 Tang H, Moro A, Feng W. et al. Giant cell tumors combined with secondary aneurysmal bone cysts are more likely to develop postoperative recurrence: a retrospective study of 256 cases. J Surg Oncol 2019; 120 (03) 359-365
    CrossrefPubMedGoogle Scholar