Zusammenfassung.
Primäre intrakranielle Germinome sind eine mögliche Ursache eines „idiopathischen” Diabetes insipidus im Kindes- und Jugendalter. Histopathologisch können sie entzündlichen Veränderungen ähneln, was zu einer Verzögerung in der Diagnosefindung führen kann. Anhand der Anamnese sowie klinischer und radiologischer Befunde von vier Patienten mit einem histologisch gesicherten, primär intrakraniellen Germinom werden weitere Probleme in der Diagnosefindung aufgezeigt.
Primary intracranial Germinoma - diagnostic difficulties demonstrated in four cases.
Primary intracranial germinoma is a possible cause of “idiopathic” diabetes insipidus in childhood and adolescence. The histopathologic appearance can be similar to inflammation, and may delay the final diagnosis. Further diagnostic difficulties are demonstrated by the use of anamnestic and clinical data as well as diagnostic imaging findings in four children with histologically proven primary intracranial germinoma.
Schlüsselwörter:
Primäre intrakranielle Germinome - Neurohypophysitis - Kindes- und Jugendalter - Magnetresonanztomographie
Key words:
Primary intracranial germinoma - Neurohypophysitis - Childhood and adolescence - Magnetic resonance imaging
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