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Synthesis 2001(5): 759-762
DOI: 10.1055/s-2001-12776
DOI: 10.1055/s-2001-12776
PAPER
© Georg Thieme Verlag Stuttgart · New York
A Short Synthesis of the Bacterial Pigments Violacein and Deoxyviolacein
Further Information
Received
30 January 2001
Publication Date:
15 October 2004 (online)
Publication History
Publication Date:
15 October 2004 (online)
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Abstract
A concise synthesis of the bacterial pigments deoxyviolacein (1a) and violacein (1b) is described in which two indole units are attached stepwise to the central pyrrolinone ring.
Key words
total synthesis - natural products - bacterial pigments - violacein - indoles
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References
LiHMDS appeared to be superior to LDA or LDA/TMSCl in the aldol reaction of 6a/b with 7