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DOI: 10.1055/s-2001-12807
© Georg Thieme Verlag Stuttgart · New York
Small Neuroendocrine Carcinoma of the Rectum Entirely Covered by an Adenomatous Component
H. Yoshikane,M.D.
Dept. of Internal Medicine
Handa City Hospital
2-29 Toyo, Handa
Aichi, 475
Japan
Fax: Fax:+ 81-569-243253
Email: E-mail:winwin@cac-net.ne.jp
Publication History
Publication Date:
31 December 2001 (online)


Figure 1 a Neuroendocrine carcinoma (NEC) of the large intestine is a rare condition with an extremely poor prognosis. At autopsy, a laterally spreading tumor (LST) 5 cm in diameter was found in the rectum in a 54-year-old woman who had multiple liver and bone metastases of unknown origin. b Cross section of the LST revealed, however, the coexistence of a whitish round tumor (arrow) beneath the brownish LST.


Figure 2Pathological examination revealed the LST to be a tubulovillous adenoma and the round tumor to be NEC. The extensive metastases resulted from the NEC which was just 1 cm in diameter (haematoxylin and eosin stain, original magnification × 12).
H. Yoshikane,M.D.
Dept. of Internal Medicine
Handa City Hospital
2-29 Toyo, Handa
Aichi, 475
Japan
Fax: Fax:+ 81-569-243253
Email: E-mail:winwin@cac-net.ne.jp
H. Yoshikane,M.D.
Dept. of Internal Medicine
Handa City Hospital
2-29 Toyo, Handa
Aichi, 475
Japan
Fax: Fax:+ 81-569-243253
Email: E-mail:winwin@cac-net.ne.jp


Figure 1 a Neuroendocrine carcinoma (NEC) of the large intestine is a rare condition with an extremely poor prognosis. At autopsy, a laterally spreading tumor (LST) 5 cm in diameter was found in the rectum in a 54-year-old woman who had multiple liver and bone metastases of unknown origin. b Cross section of the LST revealed, however, the coexistence of a whitish round tumor (arrow) beneath the brownish LST.


Figure 2Pathological examination revealed the LST to be a tubulovillous adenoma and the round tumor to be NEC. The extensive metastases resulted from the NEC which was just 1 cm in diameter (haematoxylin and eosin stain, original magnification × 12).