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Synthesis 2001(10): 1471-1478
DOI: 10.1055/s-2001-16076
DOI: 10.1055/s-2001-16076
PAPER
© Georg Thieme Verlag Stuttgart · New York
Desymmetrization Reactions: A Convenient Synthesis of Aromatic Diamide Diamines
Further Information
Received
29 January 2001
Publication Date:
23 September 2004 (online)
Publication History
Publication Date:
23 September 2004 (online)
Abstract
A two-step process for the synthesis of various diamide diamines derived from 1,n-diamino benzene compounds is described. The amidation reaction is simple, mild, involves readily available bis(N-acylthiazolidine-2-thione) derivatives as acylating agents and requires only stoichiometric equivalents of diamine and acylating agents.
Key words
regioselectivity - aromatic diamines - acylation - diamides - N-acylthiazolidine-2-thione
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References
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