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Am J Perinatol 2001; 18(5): 293-298
DOI: 10.1055/s-2001-16993
DOI: 10.1055/s-2001-16993
ORIGINAL ARTICLES
Copyright © 2001 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662
Combination Thrombolytic and Anticoagulant Therapy for Bilateral Renal Vein Thrombosis in a Premature Infant
Further Information
Publication History
Publication Date:
10 September 2001 (online)


ABSTRACT
We report a premature infant with bilateral renal vein thrombosis and renal failure at 1 month of age who underwent treatment with recombinant tissue plasminogen activator and heparin sulfate. Combination thrombolytic and anticoagulation therapy was complicated by an intraventricular and intraparenchymal cerebral hemorrhage without resolution of the renal vein thrombosis. With increasing reports of successful use of this therapy for venous thrombosis, we suggest caution and continued study of its use in the premature infant and newborn.
KEYWORD
Renal vein thrombosis - TPA - prematurity - intraventricular hemorrhage