C-Vinylation of 1-Vinylpyrroles with Benzoylacetylene on Silica Gel

Boris A. Trofimov; Zinaida V. Stepanova; Lyubov N. Sobenina; Al’bina I. Mikhaleva; Igor’ A. Ushakov; Valentina N. Elokhina

doi:10.1055/s-2001-17529

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C-Vinylation of 1-Vinylpyrroles with Benzoylacetylene on Silica Gel

Boris A. Trofimov*, Zinaida V. Stepanova, Lyubov N. Sobenina, Al’bina I. Mikhaleva, Igor’ A. Ushakov, Valentina N. Elokhina
A. E. Favorsky Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences, 1, Favorsky Street, Irkutsk 664033, Russia
Fax: +39(52)396046; e-Mail: admin@irioch.irk.ru;

Abstract

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Abstract

1-Vinylpyrroles readily add to benzoylacetylene on grinding the reagents with silica gel at room temperature to form 2-(E)-(2-benzoylvinyl)-1-vinylpyrroles in 50-84% yield in a regio- and stereoselective manner.

Key words

1-vinylpyrroles - benzoylacetylene - silica gel - 2-(E)-(2-benzoylvinyl)-1-vinylpyrroles - 1,2-divinylpyrroles

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References

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