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DOI: 10.1055/s-2001-17917
Schistosomiasis and Presinusoidal Portal Hypertension
M. Willems, M.D., Ph.D.
Dept. of Hepatogastroenterology
Erasmus University Hospital Rotterdam
PO Box 2040
3000 CA Rotterdam
The Netherlands
Fax: + 31-10-4365916
Email: willems@mdl.azr.nl
Publication History
Publication Date:
18 October 2001 (online)
Figure 1 A 36-year-old Angolese man was examined because of portal hypertension of unknown origin. Physical examination revealed marked splenomegaly. Serological testing for schistosome infection was positive (enzyme-linked immunosorbent assay [ELISA] 1 : 256). A laparoscopy was performed, and both right and left liver lobes showed a pattern of diffuse and irregular white bands, suggesting fibrosis.
Figure 2 Microscopical examination of a liver biopsy showed periportal fibrosis and a schistosome egg was detected with a granulomatous reaction. Treatment with a single dose of praziquantel was given.
M. Willems, M.D., Ph.D.
Dept. of Hepatogastroenterology
Erasmus University Hospital Rotterdam
PO Box 2040
3000 CA Rotterdam
The Netherlands
Fax: + 31-10-4365916
Email: willems@mdl.azr.nl
M. Willems, M.D., Ph.D.
Dept. of Hepatogastroenterology
Erasmus University Hospital Rotterdam
PO Box 2040
3000 CA Rotterdam
The Netherlands
Fax: + 31-10-4365916
Email: willems@mdl.azr.nl
Figure 1 A 36-year-old Angolese man was examined because of portal hypertension of unknown origin. Physical examination revealed marked splenomegaly. Serological testing for schistosome infection was positive (enzyme-linked immunosorbent assay [ELISA] 1 : 256). A laparoscopy was performed, and both right and left liver lobes showed a pattern of diffuse and irregular white bands, suggesting fibrosis.
Figure 2 Microscopical examination of a liver biopsy showed periportal fibrosis and a schistosome egg was detected with a granulomatous reaction. Treatment with a single dose of praziquantel was given.