Planta Med 2001; 67(8): 748-749
DOI: 10.1055/s-2001-18343
Letter

© Georg Thieme Verlag Stuttgart · New York

Osteoblastic Proliferation Stimulating Activity of Psoralea corylifolia Extracts and Two of its Flavonoids

Dawei Wang1 , Famei Li1,*, Zhiming Jiang2
  • 1 Department of Analytical Chemistry, Shenyang Pharmaceutical University, China
  • 2 Department of Medical Experiment, General Hospital of Shenyang Military Region, China
Further Information

Publication History

October 25, 2000

January 21, 2001

Publication Date:
09 November 2001 (online)

Abstract

Psoralea corylifolia L. fruit extracts exhibited osteoblastic proliferation stimulating activity in UMR106 cell line cultured in vitro. The flavonoids of corylin and bavachin were isolated and identified as active principles by activity-guided fractionation. The results suggested that Psoralea corylifolia L. fruit extracts and corylin and bavachin might stimulate bone formation or have potential activity against osteoporosis.

References

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Prof. Famei Li

Department of Analytical Chemistry

Shenyang Pharmaceutical University

Shenyang 110 016

China

Email: fameili@ihw.com.cn

Fax: +86-24-83890024