Download PDF
Facial Plast Surg 2002; 18(1): 035-040
DOI: 10.1055/s-2002-19825
Copyright © 2002 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Botulinum Toxin to Minimize Facial Scarring

David A. Sherris1, 2 , Holger G. Gassner2
  • 1Division of Facial Plastic Surgery, Mayo Clinic, Rochester, MN
  • 2Department of Otolaryngology, Mayo Graduate School of Medicine, Rochester, MN
Further Information

Publication History

Publication Date:
29 January 2002 (online)

Also available at
    Permissions and Reprints

ABSTRACT

Botulinum toxin injection has been used for a variety of indications in humans, including blepharospasm and hyperfunctional facial lines. This article describes a novel formulation of botulinum toxin, which supplies immediate feedback to the injecting physician. Additionally, recent findings are described that indicate the immediate injection of botulinum toxin into the muscles underlying a wound can improve the cosmetic outcome of the facial cutaneous scar. Future applications of these findings are discussed.

KEYWORD

Botulinum toxin - scar - wound healing - facial scar

REFERENCES

  • 1 Cloquet J H. Traité d'Anatomie Descriptive.  Paris: Libraire de Crochard 1832: 313
    Search in Google Scholar
  • 2 Dupuytren G. Traité Théorique et Pratique des Armes de Guerre, Vol 2.  Paris: Baillére 1834: 60-66
    Search in Google Scholar
  • 3 Langer K. On the anatomy and physiology of the skin: I. The cleavability of the skin.  Br J Plast Surg . 1978;  31 3
    CrossrefPubMedSearch in Google Scholar
  • 4 Borges A F. Elective Incisions and Scar Revision.  Boston: Little, Brown 1973: 29
    Search in Google Scholar
  • 5 Larrabee Jr W F, Sherris D A. Principles of Facial Reconstruction.  Philadelphia: Lippincott-Raven 1995: 7
    Search in Google Scholar
  • 6 McCarthy J G. Plastic Surgery, Vol 1.  Philadephia: WB Saunders 1990: 43-44
    Search in Google Scholar
  • 7 Courtiss E H, Longacre J J, DeStafano G A, Loredana B, Holmstrand K. The placement of elective skin incisions.  Plast Reconstr Surg . 1963;  31 31
    PubMedSearch in Google Scholar
  • 8 Sherris D A, Larrabee Jr F W, Murakami C S. Management of scar contractures, hypertrophic scars and keloids.  Otolaryngol Clin North Am . 1995;  28 1057
    PubMedSearch in Google Scholar
  • 9 Physicians Desk Reference. Montvale, NJ: Medical Economics; . 2000 54: 495-497
    Search in Google Scholar
  • 10 Carruthers A, Keine K, Carruthers J. Botulinum A exotoxin use in clinical dermatology.  J Am Acad Dermatol . 1996;  34 788
    PubMedSearch in Google Scholar
  • 11 Scott A B. Botulinum toxin injection into extraocular muscles as an alternative to strabismus surgery.  Ophthalmology . 1980;  87 1004-1049
    PubMedSearch in Google Scholar
  • 12 Hallett M. One man's poison-clinical applications of botulinum toxin (editorial).  N Engl J Med . 1999;  341 118-120
    CrossrefPubMedSearch in Google Scholar
  • 13 Scott A B, Suzuki D. Systemic toxicity of botulinum toxin by intramuscular injection in the monkey.  Mov Disord . 1988;  3 333
    CrossrefPubMedSearch in Google Scholar
  • 14 Gassner H G, Sherris D A. Addition of anesthetic agent enhances the predictability of botulinum toxin injections.  Mayo Clin Proc . 2000;  75 701-704
    PubMedSearch in Google Scholar
  • 15 Karatassas A, Morris R G, Slavotinek A H. The relationship between regional blood flow and absorption of lidocaine.  Aust NZ J Surg . 1993;  63 766-771
    PubMedSearch in Google Scholar
  • 16 Gassner H G, Sherris D A, Otley C C. Treatment of facial wounds with botulinum toxin A improves cosmetic outcome in primates.  Plast Reconstr Surg . 2000;  105 1948-1953
    CrossrefPubMedSearch in Google Scholar
  • 17 Carruthers A, Carruthers J. Aesthetic indications for botulinum toxin injections.  Plast Reconstr Surg . 1995;  96 437-438
    PubMedSearch in Google Scholar