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DOI: 10.1055/s-2002-20254
© Georg Thieme Verlag Stuttgart · New York
New Lupane Glycosides from Pulsatilla chinensis
Publication History
February 10, 2001
June 17, 2001
Publication Date:
22 February 2002 (online)
Abstract
Two new lupane glycosides along with five known triterpenoids were isolated from the roots of Pulsatilla chinensis (Ranunculaceae). The structures of the new glycosides were determined to be 3-O-β-D-glucopyranosyl(1→3)-α-L-arabinopyranosyl-23-hydroxybetulinic acid 28-O-α-L-rhamnopyranosyl(1→4)-β-D-glucopyranosyl(1→6)-β-D-glucopyranosyl ester (pulsatilloside D, 6) and 3-O-[β-D-glucopyranosyl(1→4)][α-L-rhamnopyranosyl(1→2)]-α-L-arabinopyranosyl-23-hydroxybetulinic acid 28-O-α-L-rhamnopyranosyl(1→4)-β-D-glucopyranosyl(1→6)-β-D-glucopyranosyl ester (pulsatilloside E, 7) by spectroscopic analysis and chemical methods. The compounds were evaluated for cytotoxic activities against K-562 human leukemia and HeLa cells.
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Prof. Chun-Tao Che
School of Chinese Medicine
The Chinese University of Hong Kong
Shatin
Hong Kong
Email: chect@cuhk.edu.hk
Fax: +852-2603-7203
Phone: +852-2609-8130