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Semin Liver Dis 2002; 22(1): 097-102
DOI: 10.1055/s-2002-23209
DIAGNOSTIC PROBLEMS IN HEPATOLOGY

Copyright © 2002 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

A 25-Year-Old Man with a Large Hepatic Tumor and Multiple Nodular Lesions

Fotis Iordanidis1 , Prodromos Hytiroglou1 , Antonios Drevelegas2 , Fotis Kodonas3 , Ioannis Ioannidis2 , Helen Nenopoulou1 , Constantine S. Papadimitriou1
  • 1Department of Pathology, Aristotle University Medical School, Thessaloniki, Greece
  • 2Department of Radiology, Aristotle University Medical School, Thessaloniki, Greece
  • 3Department of Surgery, Aristotle University Medical School, Thessaloniki, Greece
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Publication History

Publication Date:
27 March 2002 (online)

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ABSTRACT

A 25-year-old man without a prior history of liver disease presented with an 18-cm tumor of the right hepatic lobe, which was associated with multiple nodular lesions in the remaining parenchyma. The histologic and immunohistochemical features of the neoplasm were those of a poorly differentiated leiomyosarcoma with epithelioid features. The nodular lesions measured up to 4 cm in greatest dimension and had gross and microscopic features of focal nodular hyperplasia. This case suggests that multiple focal nodular hyperplasia may occasionally represent a parenchymal reaction to abnormal blood supply developing within the liver as a consequence of an enlarging malignant tumor.

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