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DOI: 10.1055/s-2002-28271
Navigator-gated and real-time motion corrected
free-breathing MR Imaging of
myocardial late enhancement
MRT der myokardialen Spätanreicherung während freier Atmung unter Einsatz einer prospektiven Navigatortechnologie mit Echtzeit-Schichtnachführung
Publication History
19. 2. 2002
after revision 11. 3. 2002
Publication Date:
07 May 2002 (online)
![](https://www.thieme-connect.de/media/roefo/200205/lookinside/thumbnails/10.1055-s-2002-28271-1.jpg)
Abstract
Purpose: A new magnetic resonance imaging approach for detection of myocardial late enhancement during free-breathing was developed. Methods and Results: For suppression of respiratory motion artifacts, a prospective navigator technology including real-time motion correction and a local navigator restore was implemented. Subject specific inversion times were defined from images with incrementally increased inversion times acquired during a single dynamic scout navigator-gated and real-time motion corrected free-breathing scan. Subsequently, MR-imaging of myocardial late enhancement was performed with navigator-gated and real-time motion corrected adjacent short axis and long axis (two, three and four chamber) views. This alternative approach was investigated in 7 patients with history of myocardial infarction 12 min after i. v. administration of 0.2 mmol/kg body weight gadolinium-DTPA. Conclusion: With the presented navigator-gated and real-time motion corrected sequence for MR-imaging of myocardial late enhancement data can be completely acquired during free-breathing. Time constraints of a breath-hold technique are abolished and optimized patient specific inversion time is ensured.
Zusammenfassung
Zielsetzung: Das Ziel der Arbeit war die Entwicklung einer MR-Sequenz, welche eine Datenaufnahme während freier Atmung zur MR-Vitalitätsdiagnostik erlaubt. Methoden und Ergebnisse: Zur Eliminierung der Atemartefakten bei einer Datenaufnahme während freier Atmung wurde eine prospektive Navigator-Technologie mit Echtzeit-Schichtnachführung und ein lokaler Navigator-Rückstellpuls in eine MR-Sequenz zur Diagnostik der myokardialen Spätanreicherung implementiert. Patientenspezifische Inversions-Zeiten wurden mit einer vorgeschalteten Inversionszeit-Bestimmungssequenz mit variablen Inversionszeiten ermittelt. Diese Sequenz wurde ebenfalls während freier Atmung angefertigt. Die Diagnostik der myokardialen Spätanreicherung erfolgte mit der patientenspezifischen Inversionszeit und einer Schichtführung im Zwei-, Drei- und Vierkammerblick sowie in der kurzen Achse. 7 Patienten mit Myokardinfarkt wurden 12 Minuten nach Applikation von 0,2 mmol/kg Körpergewicht Gd-DTPA i. v. untersucht. Schlussfolgerung: Die neue MR-Sequenz mit Navigator-Technologie und Echtzeit-Schichtnachführung erlaubt die Datenakquisition zu Diagnostik der myokardialen Spätanreicherung einschließlich der Bestimmung der patientenspezifischen Inversionszeit während freier Atmung. Die Limitationen einer Atemanhalte-Technik werden durch diese neue Technik behoben.
Key words
Magnetic Resonance Imaging - Myocardial Viability - Contrast enhancement - Navigator technology
Schlüsselwörter
Magnetic Resonance Imaging - Myocardial Viability - Contrast enhancement - Navigator technology
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Dr. med. Elmar Spuentrup
Department of Diagnostic Radiology, University Hospital, Technical University of Aachen
Pauwelsstraße 30
52057 Aachen
Germany
Phone: + 49-241-8088332
Fax: + 49-241-8082411
Email: spuenti@rad.rwth-aachen.de