N-Ethylpiperidine Hypophosphite Mediated Intermolecular Radical Carbon-Carbon Bond Forming Reaction in Water

Abstract

N-Ethylpiperidine hypophosphite mediated radical addition reactions to electron deficient alkenes in aqueous media have been developed. The reactions afford high isolated yields of addition products without using a large excess of alkenes.

Key words

radical reactions - addition reactions - alkenes - alkyl halides - water

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For intramolecular C-C bond formation in water, see ref. [4b]