Abstract
From the roots of Salvia eriophora (Lamiaceae), a new compound, 4,14-dihydroxysaprorthoquinone, was isolated in addition to ten known diterpenoids. The structure of the new compound was established by spectroscopic analysis. The crude extract of the plant and the isolated diterpenoids were tested for their cardiovascular activities using Wistar Albino rats. Activity was demonstrated in the crude extract and in 4,14-dihydroxysaprorthoquinone, aethiopinone, ferruginol, 4,12-dihydroxysapriparaquinone, and 6,7-dehydroroyleanone.
Key words
Salvia eriophora
- Lamiaceae - abietane and rearranged abietane diterpenes - vasodepressor effect
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Prof. Dr. Ayhan Ulubelen
Faculty of Pharmacy
University of Istanbul
34452 Beyazıt-Istanbul
Turkey
Fax: +90212-5190812
eMail: aulubelen@yahoo.com
