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Planta Med 2002; 68(9): 822-826
DOI: 10.1055/s-2002-34416
Original Paper
Natural Product Chemistry
© Georg Thieme Verlag Stuttgart · New York

Fatty Acid Esters of Triterpenoids and Steroid Glycosides from Gambeya africana

Jean Wandji1 , Francois Tillequin2 , Dulcie A. Mulholland3 , Jean-Duplex Wansi1 , Tanee Z. Fomum1 , Victorine Fuendjiep4 , Francine Libot2 , Nole Tsabang4
  • 1Department of Organic Chemistry, University of Yoaunde-1, Cameroon
  • 2Laboratoire de Pharmacognosie, UMR/CNRS No-8638, Université René-Descartes, Faculté de Pharmacie, Paris, France
  • 3Department of Chemistry, Natural Products Research Group, University of Natal, Durban, Republic of South Africa
  • 4Centre de recherche en plantes médicinales et médecine traditionnelle, IMPM, Yaoundé, Cameroun
Further Information

Publication History

Received: December 21, 2001

Accepted: February 24, 2002

Publication Date:
30 September 2002 (online)

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Abstract

Chemical studies of the CH2Cl2-MeOH extract of the seeds of Gambeya africana (Baker) Pierre led to the isolation of 15 compounds. Their structures were established on the basis of spectroscopic methods and chemical reactions. They comprised five new fatty acid esters of erythrodiol, [3β-octacosanoyloxy-12-oleanen-28-ol, 3β-triacontanoyloxy-12-oleanen-28-ol, 3β-dotriacontanoyloxy-12-oleanen-28-ol, 3β-tetratriacontanoyloxy-12-oleanen-28-ol and 3β-hexatriacontanoyloxy-12-oleanen-28-ol], one new steroidal glycoside, [3β-O-β-xylopyranosylchondrillasterol] and nine known compounds, (3β-octadecanoyloxy-12-oleanene, 3β-eicosanoyloxy-12-oleanene, 3β-docosanoyloxy-12-oleanene, 3β-acetoxy-12-oleanene, erythrodiol, 28-hydroxy-β-amyrone, chondrillasterol , chondrillasterone and 3β-O-β-glucopyranosylchondrillasterol).

Key words

Gambeya africana - Sapotaceae - seeds - fatty acid esters - erythrodiol - triterpenoids - chondrillasterol - steroid glycosides

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Prof. Dr. Jean Wandji

Department of Organic Chemistry

University of Yaounde-1

Faculty of Science

PO.Box 812 Yaounde

Cameroon

Email: jeanwandji@yahoo.fr

Fax: +237-223 53 86

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