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Psychiatr Prax 2003; 30(2): 89-92
DOI: 10.1055/s-2003-37440
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© Georg Thieme Verlag Stuttgart · New York

Organische depressive Störung bei Cushing-Syndrom - ein Fallbericht

Organic Depressive Disorder Caused by Cushing's Syndrome - Case ReportKathrin  Rolle1 , Andrea  Kopf1 , Matthias  C.  Angermeyer1
  • 1Klinik und Poliklinik für Psychiatrie der Universität Leipzig
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Publication History

Publication Date:
24 February 2003 (online)

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Zusammenfassung

Berichtet wird der Fall einer 35-jährigen Patientin, die neben zunehmender Schwere des depressiven Krankheitsbildes Symptome eines Cushing-Syndroms zeigte. Im Schädel-MRT wurde ein Mikroadenom der Hypophyse festgestellt. Nach transsphenoidaler Adenektomie kam es zur Normalisierung des Serumkortisolspiegels und zu einer rapiden Verbesserung des psychischen und allgemeinkörperlichen Zustandes. Depressive Syndrome erfordern den Ausschluss einer organischen Ursache.

Abstract

We report a case of 35-year old female patient with recurrent depressive disorder and Cushing's syndrome. MRI of the brain revealed a microadenoma of the pituitary gland. After neurosurgery the serum levels of cortisol went back to normal and the clinical and mental state of the patient improved rapidly. Depressive episodes require additional diagnostics to exclude somatic etiology.

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Dr. med. Kathrin Rolle

Klinik und Poliklinik für Psychiatrie · Universität Leipzig

Johannisallee 20

04317 Leipzig

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