Antifungal and Antioxidant Compounds from the Root Bark of Fagara zanthoxyloides

Abstract

Phytochemical investigation of the CH₂Cl₂ extract of Fagara zanthoxyloides Lam. (Rutaceae) led to the isolation of eleven compounds. One phenylethanoid derivative is a new natural product. The isolation of the antifungal and the antioxidant compounds was monitored by direct TLC bioautographic assays. The structures of the isolated compounds were elucidated by classical spectroscopic methods including UV, NMR, MS and HR-MS.

Key words

Fagara zanthoxyloides - Rutaceae - phenylethanoid derivative - Cladosporium cucumerinum - Candida albicans - Bacillus subtilis - free radical scavengers

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