Aromatic imines derived in situ from aryl aldehydes and aryl
amines undergo smoothly, cyclization with alkynes on the surface
of montmorillonite clay impregnated with copper(I) bromide under
solvent-free conditions to produce 2,4-disubstituted quinolines
in high yields with excellent selectivity. The reaction rates and yields
are significantly improved by employing microwave irradiation.
microwave - aryl imines - alkynes - substituted
quinolines
