Synthesis of Unsymmetrical β-Enamino Ketones

Abstract

A convenient procedure for modification of β-enaminones by α-C-acylation and subsequent acidic cleavage is described. The unsymmetrical β-enamino ketones obtained in this way could be hydrolyzed to provide an entry towards various unsymmetrical 1,3-diketones.

enaminones - C-acylation - cleavage - 1,3-diketones - unsymmetrical

References

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Dr Atanas Venkov passed away suddenly on July 21st, 2003, aged 62.

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