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Synthesis 2003(17): 2667-2670  
DOI: 10.1055/s-2003-42435
PAPER
© Georg Thieme Verlag Stuttgart · New York

Cross Mannich Reaction of Aldehydes; Efficient Synthesis of Substituted Pyridines

Andreas Winter, Nikolaus Risch*
Universität Paderborn, Fakultät für Naturwissenschaften, Department Chemie, Warburger Str. 100, 33098 Paderborn, Germany
Fax: +49(5251)603245; e-Mail: nr@chemie.upb.de;
Further Information

Publication History

Received 26 September 2003
Publication Date:
14 October 2003 (online)

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Abstract

Symmetrically and unsymmetrically substituted pyridines were obtained in highly efficient one-pot procedures starting from α-unbranched aldehydes and iminium salts.

Key words

aldehydes - domino reactions - Mannich bases - pyridines - imines

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