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DOI: 10.1055/s-2003-43468
Demenz
DementiaPublication History
Publication Date:
10 November 2003 (online)
Weiterbildungsziele
In diesem Beitrag sollen folgende Weiterbildungsziele vermittelt werden:
1. Das neue Interesse an den Demenzen
2. Diagnostik der Demenzen
2.1 Neuropsychologische Testung
2.2 Erfassung der Alltagskompetenz
2.3 Pseudodemenz und leichte kognitive Störung
2.4 Organische Diagnostik
3. Die primären (oder degenerativen) Demenzen
3.1 Alzheimer-Demenz (AD)
3.2 Demenz mit Lewy-Körperchen (DLB)
3.3 Frontotemporale Demenz (FTD)
4. Antidementive Therapie
4.1 Cholinesterasehemmer
4.2 Memantine und andere Substanzen
5. Kernaussagen
Literatur
- 1 Sass H, Wittchen H U, Zaudig M. Diagnostisches und Statistisches Manual Psychischer Störungen. - DSM-IV. Göttingen: Hogrefe 1996
- 2 Folstein M F, Folstein S E, McHugh P R. „Mini-Mental-State”. J Psychiatr Res. 1975; 12 189-198
- 3 Calabrese P, Kessler J. DemTect zur Demenzdiagnostik. Testvorlage Karlsruhe: Pfizer & Frankfurt: Esai 2000
- 4 Ihl R, Weyer G. Alzheimer's Disease Assessment Scale (ADAS). Deutsche Bearbeitung. Weinheim: Beltz 1993
- 5 Reisberg B, Finkel S, Overall J. et al . The Alzheimer's disease activities of daily living international scale (ADL-IS). Int Psychogeriatr. 2001; 13 163-181
- 6 Petersen R C, Doody R, Kurz A. Current concepts in mild cognitive impairment. Arch Neurol. 2001; 58 1985-1992
- 7 Hulstaert F, Blennow K, Ivanoui A. et al . Improved discrimination of AD patients using beta-amyloid (1 - 42) and tau levels in CSF. Neurology. 1999; 52 1555-1562
- 8 Lobotesis K, Fenwick J D, Phipps A. et al . Occipital hypoperfusion on SPECT in dementia with Lewy bodies but not AD. Neurology. 2001; 56 643-649
- 9 Minoshima S, Foster M L, Sima A A. et al . Alzheimer's disease versus dementia with Lewy bodies: cerebral metabolic distinction with autopsy confirmation. Ann Neurol. 2001; 50 358-365
- 10 Campion D, Dumanchin C, Hannequin D. et al . Early-onset autosomal dominant Alzheimer disease: prevalence, genetic heterogeneity, and mutation spectrum. Am J Hum Genet. 1999; 65 664-670
- 11 Hy L X, Keller D M. Prevalence of AD among whites: a summary by levels of severity. Neurology. 2000; 55 198-204
- 12 Nussbaum R L, Ellis C E. Alzheimer's disease and Parkinson's disease. N Engl J Med. 2003; 348 1356-1364
- 13 Barber R, Panikkar A, McKeith I G. Dementia with Lewy bodies: diagnosis and treatment. Int J Geriatr Psychiatry. 2001; 16 S12-S18
- 14 McKeith I G, Galasko G, Kosaka K. et al . Consensus guidelines for the clinical and pathological diagnosis of dementia with Lewy bodies (DLB). Neurology. 1996; 47 1113-1124
- 15 Wallesch C W. Leitlinien zur Diagnostik bei Patienten mit Demenz. Akt Neurol. 2001; 28 201-207
- 16 Papka M, Rubio A, Schiffer R B. A review on Lewy body disease, an emerging concept of cortical dementia. J Neuropsychiatr Clin Neurosci. 1998; 10 267-279
- 17 Ratnavalli E, Brayne C, Dawson K. et al . The prevalence of frontotemporal dementia. Neurology. 2002; 58 1615-1621
- 18 McKhann G, Marilyn S, Grossmann M. et al . Clinical and pathological diagnosis of frontotemporal dementia. Arch Neurol. 2001; 58 1803
- 19 Diehl J, Kurz A. Frontotemporal dementia: patient characteristics, cognition, and behavior. Int J Geriatr Psychiatry. 2002; 17 914-918
- 20 Broe M, Hodges J R, Schofield E. et al . Staging disease severity in pathologically confirmed cases of frontotemporal dementia. Neurology. 2003; 60 1005-1011
- 21 Pickering-Brown S, Baker M, Yen S H. et al . Pick's disease is associated with mutations in the tau gene. Ann Neurol. 2000; 48 859-867
- 22 McKeith I, Del Ser T, Spano P. et al . Efficacy of rivastigmine in dementia with Lewy bodies: a randomised, double blind, placebo-controlled international study. Lancet. 2000; 356 2031-2036
- 23 Winblad D, Poritis N. Memantine in severe dementia. Results of the M-Best study. Int J Geriatr Psychiatry. 1999; 14 135-146
Priv.-Doz. Dr. rer. nat. Dipl.-Psych. Rolf R. Diehl
Neurologische Klinik · Alfried Krupp Krankenhaus
Alfried-Krupp-Straße 21
45117 Essen
Email: Rolf.Diehl@Krupp-Krankenhaus.de