The Formation of β-Lactam Derivatives through the Reaction of Dibenzoyl­acetylene and Aryl Isocyanates in the Presence of Trivalent Phosphorus Nucleophiles

Abstract

An effective route to novel β-lactams is described. This involves reaction of dibenzoylacetylene and phenyl isocyanate or phenylsulfonyl isocyanate in the presence of trivalent phosphorus nucleophiles.

triphenylphosphine - trialkyl phosphates - dibenzoylacetylene - aryl isocyanate - β-lactams

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