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DOI: 10.1055/s-2004-821077
© Georg Thieme Verlag KG Stuttgart · New York
Pre- and Postoperative Assessment of Left Ventricular Function by Magnetic Resonance Imaging and 2-D-Echocardiography in Patients Undergoing Left Ventricular Aneurysmectomy
Publication History
Received January 19, 2003
Publication Date:
06 October 2004 (online)
Abstract
Background: Left ventricular (LV) aneurysms may complicate myocardial infarctions. Reliable quantification of LV functional parameters is mandatory to predict clinical outcome in patients undergoing LV aneurysmectomy. We compared global LV function measured by magnetic resonance (MR) and 2-D-echocardiography in patients before and after aneurysmectomy. Methods: 31 patients (23 male), mean age 64 (range 35 - 85) years with an LV aneurysm (25/31 anterior MI, 5/31 inferior MI, 1/31 both) were enrolled. MR and echocardiography were performed directly before and 3 - 65 (median 8) days after surgery. MR studies were performed on a 1.5 Tesla scanner. End-diastolic and end-systolic volumes and diameters (EDV/ESV, EDD/ESD), ejection fraction (EF) and stroke volume (SV) were determined. Echocardiography was performed to determine EF, EDD and ESD. NYHA class was assessed before and 3 months after surgery. Results: After aneurysmectomy MR analysis showed a decrease in EDV (255 ± 68 ml to 202 ± 59 ml) (p < 0.001) and ESV (186 ± 71 ml to 134 ± 53 ml; p < 0.001); EF increased (28 ± 10 % to 35 ± 12 %; p < 0.001); EDD/ESD decreased (p < 0.01). Compared to echocardiography, a low correlation was found in EF before/after surgery r = 0.76/r = 0.69 and ESD r = 0.43/r = 0.60, respectively. In EDD a good correlation was found before surgery (r = 0.81), and a lower correlation after surgery (r = 0.72). NYHA class improved from 3.0 ± 0.5 before to 1.8 ± 0.8 after operation (p < 0.001). Conclusion: Resection of an LV aneurysm results in a mean improvement of 25 % in LV function, and improved clinical outcome. In asymmetric ventricles with aneurysms MR proved to be superior as a sensitive and non-invasive tool compared to conventional 2-D-echocardiography.
Key words
Magnetic resonance imaging - echocardiography - LV function - LV aneurysm
References
- 1 Baur L H, Schipperheyn J J, van der Wall E E. et al . Regional myocardial shape alterations in patients with anterior myocardial infarction. Int J Card Imaging. 1996; 12 89-96
- 2 Bellenger N G, Burgess M I, Ray S G. et al . Comparison of left ventricular ejection fraction and volumes in heart failure by echocardiography, radionuclide ventriculography and cardiovascular magnetic resonance. Are they interchangeable?. Eur Heart J. 2000; 21 1387-1396
- 3 Buck T, Hunold P, Wentz K U, Tkalec W, Nesser H J, Erbel R. Tomographic three-dimensional echocardiographic determination of chamber size and systolic function in patients with left ventricular aneurysm: comparison to magnetic resonance imaging, cineventriculography, and two-dimensional echocardiography. Circulation. 1997; 96 4286-4297
- 4 Di Donato M, Sabatier M, Montiglio F. et al . Outcome of left ventricular aneurysmectomy with patch repair in patients with severely depressed pump function. Am J Cardiol. 1995; 76 557-561
- 5 Dor V, Saab M, Coste P, Kornaszewska M, Montiglio F. Left ventricular aneurysm: a new surgical approach. J Thorac Cardiov Surg. 1989; 37 11-19
- 6 Dor V, Sabatier M, Di Donato M, Maioli M, Toso A, Montiglio F. Late hemodynamic results after left ventricular patch repair associated with coronary grafting in patients with postinfarction akinetic or dyskinetic aneurysm of the left ventricle. J Thorac Cardiov Surg. 1995; 110 1291-1301
- 7 Grossmann W. Cardiac hypertrophy: a useful adaption or pathologic process?. Am J Med. 1980; 69 567-584
- 8 Guccione J M, Moonly S M, Moustakidis P. et al . Mechanism underlying mechanical dysfunction in the border zone of left ventricular aneurysm: a finite element model study. Ann Thorac Surg. 2001; 71 654-662
- 9 Kim R J, Wu E, Rafael A. et al . The use of contrast enhanced magnetic resonance imaging to identify reversible myocardial dysfunction. N Engl J Med. 2000; 343 1445-1453
- 10 Lorenz C H, Walker E S, Morgan V L, Klein S S, Graham Jr T P. Normal human right and left ventricular mass, systolic function and gender differences by cine magnetic resonance imaging. J Cardiovasc Magn Reson. 1999; 1 7-21
- 11 Mitchell G F, Lamas G A, Vaughan D E, Pfeffer M A. Left ventricular remodeling in the year after first anterior myocardial infarction. Quantitative analysis of contractile segment lengths and ventricular shape. JACC. 1992; 19 1136-1144
- 12 Muhlberger V, Knapp E, Hopferweiser T, Scharfetter H. Functional cardiac assessment before and after left ventricular anterior aneurysm repair, especially as related to work capacity. Cardiology. 1988; 75 108-116
- 13 Ratcliffe M B, Wallace A W, Salahieh A, Hong J, Ruch S, Hall T S. Ventricular volume, chamber stiffness, and function after anteroapical aneurysm plication in the sheep. J Thorac Cardiov Surg. 2000; 119 115-124
- 14 Rominger M B, Bachmann G F, Geuer M. et al . Accuracy of right- and left-ventricular muscle mass determinants by cine MRI in breath-hold technique. Rofo Fortschr Geb. 2000; 172 23-32
- 15 Schiller N B, Shah P M, Crawford M. et al . Recommendations of quantification of the left ventricle by two-dimensional echocardiography. American Society of Echocardiography Committee on Standards, Subcommittee on Quantification of Two-Dimensional Echocardiograms. J Am Soc Echocardiogr. 1989; 2 358-367
- 16 Sechtem U, Pflugfelder P W, Gould R G, Cassidy M M, Higgins C B. Measurement of right and left ventricular volumes in healthy individuals with cine MR imaging. Radiology. 1987; 163 697-702
- 17 Semelka R C, Tomei E, Wagner S. et al . Interstudy reproducibility of dimensional and functional measurements between cine magnetic resonance imaging studies in the morphologically abnormal left ventricle. Am Heart J. 1990; 119 1367-1373
- 18 Visser C A, Kann G, Meltzer R S. et al . Assessment of left ventricular aneurysm resectability by two-dimensional echocardiography. Am J Cardiol. 1985; 56 857-860
- 19 Wyatt H L, Meerbaum S, Heng Gueret M KP, Corday E. Cross-sectional echocardiography, III: analysis of mathematic models for quantifying volume of symmetric and asymmetric left ventricles. Am Heart J. 1980; 100 821-828
- 20 Zardini P, Marino P, Golia G M, Anselmi M, Castelli M. Ventricular remodeling and infarct expansion. Am J Cardiol. 1993; 72 98-106
Dr. Thorsten Dill
Department of Cardiology/Cardiovascular Magnetic Resonance, Kerckhoff Heart Center
Benekestraße 2 - 8
61231 Bad Nauheim
Germany
Phone: + 4960329960
Fax: + 49 6 03 29 96 22 98
Email: t.dill@kerckhoff-klinik.de