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Synthesis 2004(8): 1253-1256
DOI: 10.1055/s-2004-822383
DOI: 10.1055/s-2004-822383
PAPER
© Georg Thieme Verlag Stuttgart · New York
Cadmium Chloride: An Efficient Catalyst for One-Pot Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones
Further Information
Received
13 February 2004
Publication Date:
19 May 2004 (online)
Publication History
Publication Date:
19 May 2004 (online)
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Abstract
Biginelli reaction was carried out using cadmium chloride as a catalyst to obtain the dihydropyrimidones in excellent yields. This condensation was applicable to various aldehydes with ethyl acetoacetate and urea in acetonitrile at reflux temperature.
Key words
cadmium chloride - ethyl acetoacetate - urea - multicomponent reaction - dihydroprimidones
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