Endoscopy 2004; 36(12): 1054-1059
DOI: 10.1055/s-2004-826041
Original Article
© Georg Thieme Verlag KG Stuttgart · New York

Comparison of Capsule Endoscopy and Magnetic Resonance Imaging for the Detection of Polyps of the Small Intestine in Patients with Familial Adenomatous Polyposis or with Peutz-Jeghers’ Syndrome

R.  Caspari1 , M.  von Falkenhausen2 , C.  Krautmacher2 , H.  Schild2 , J.  Heller1 , T.  Sauerbruch1
  • 1Department of Internal Medicine I, Rheinische Friedrich-Wilhelms-Universität Bonn, Germany
  • 2Department of Radiology, Rheinische Friedrich-Wilhelms-Universität Bonn, Germany
Further Information

Publication History

Submitted 14 July 2004

Accepted after Revision 8 August 2004

Publication Date:
01 December 2004 (online)

Background and Study Aims: We have conducted a study to compare the diagnostic yields of magnetic resonance imaging (MRI) and capsule endoscopy for the detection of small-bowel polyps in patients with inherited polyposis syndromes.
Patients and Methods: MRI was performed in 20 patients, with either Peutz-Jeghers’ syndrome (PJS; n = 4) or familial adenomatous polyposis (FAP; n = 16), and capsule endoscopy was done the next day. The number, size, and location of polyps were analyzed.
Results: Overall, 448 polyps ranging from about 1 mm to 30 mm in size were detected in eight patients by capsule endoscopy, whereas with MRI only 24 polyps all bigger than 5 mm could be seen in the four PJS patients.
Conclusions: Polyps bigger than 15 mm were detected similarly with capsule endoscopy and MRI, whereas smaller polyps were seen much more often with capsule endoscopy. Polyps smaller than 5 mm were exclusively seen with capsule endoscopy. However, location of the detected polyps and determination of their exact sizes was more accurate by MRI.

References

  • 1 Umschaden H W, Szolar D, Gasser J. et al . Small-bowel disease: comparison of MR enteroclysis images with conventional enteroclysis and surgical findings.  Radiology. 2000;  215 717-725
  • 2 Schmidt T, Reinshagen M, Brambs H J. et al . Comparison of conventional enteroclysis, intestinal ultrasound and MRI-enteroclysis for determining changes in the small intestine and complications in patients with Crohn’s disease.  Z Gastroenterol. 2003;  41 641-648
  • 3 Costamagna G, Shah S K, Riccioni M E. et al . A prospective trial comparing small bowel radiographs and video capsule endoscopy for suspected small bowel disease.  Gastroenterology. 2002;  123 999-1010
  • 4 Ell C, Remke S, May A. et al . The first prospective controlled trial comparing wireless capsule endoscopy with push enteroscopy in chronic gastrointestinal bleeding.  Endoscopy. 2002;  34 685-689
  • 5 Eliakim R, Fischer D, Suissa A. et al . Wireless capsule video endoscopy (CVE) is a superior diagnostic tool in comparison to barium follow through and computerised tomography (CT) in patients with suspected Crohn’s disease.  Eur J Gastroenterol Hepatol. 2003;  15 363-367
  • 6 Iddan G, Meron G, Glukhovsky A, Swain P. Wireless capsule endoscopy.  Nature. 2000;  405 417
  • 7 Swain P. Wireless capsule endoscopy.  Gut. 2003;  52 Suppl 4 48-50
  • 8 Schulmann K, Schmiegel W. Capsule endoscopy for small bowel surveillance in hereditary intestinal polyposis and non-polyposis syndromes.  Gastrointest Endosc Clin N Am. 2004;  14 149-158
  • 9 Giardiello F M, Brensinger J D, Tersmette A C. et al . Very high risk of cancer in familial Peutz-Jeghers’ syndrome.  Gastroenterology.. 2000;  119 1447-1453
  • 10 McGarrity T J, Kulin H E, Zaino R J. Peutz-Jeghers’ syndrome.  Am J Gastroenterol. 2000;  95 596-604
  • 11 Parsi M A, Burke C A. Utility of capsule endoscopy in Peutz-Jeghers’ syndrome.  Gastrointest Endosc Clin N Am.. 2004;  14 159-167

R. Caspari, M. D.

Department of Internal Medicine I, Universitätsklinikum Bonn

Sigmund Freud Straße 25 · 53105 Bonn · Germany

Fax: + 49-228-2875849

Email: reiner.caspari@ukb.uni-bonn.de