Hepatitis B Virus Kinetics and Mathematical Modeling

Alan S. Perelson; Ruy M. Ribeiro

doi:10.1055/s-2004-828673

Seminars in Liver Disease, Table of Contents

Semin Liver Dis 2004; 24: 11-16
DOI: 10.1055/s-2004-828673

Published in 2004 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Hepatitis B Virus Kinetics and Mathematical Modeling

Alan S. Perelson¹ , Ruy M. Ribeiro¹ ^, ²

¹Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico
²Department of Zoology, Oxford University, Oxford, United Kingdom

Abstract

In this article, we review modeling and interpretation of kinetics data obtained from patients with chronic hepatitis B virus infection that has been treated with lamivudine, adefovir dipivoxil, and lamivudine plus famciclovir combination therapy.

KEYWORDS

Hepatitis B virus - modeling - viral kinetics

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References

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Alan S PerelsonPh.D.

Theoretical Biology and Biophysics, MS K710, Los Alamos National Laboratory

Los Alamos, NM 87545

Email: asp@lanl.gov