One-Pot Clean Synthesis of 1,8-Dioxo-decahydroacridines Catalyzed by p-Dodecylbenezenesulfonic Acid in Aqueous Media

Tong-Shou Jin; Jian-She Zhang; Tong-Tong Guo; Ai-Qing Wang; Tong-Shuang Li

doi:10.1055/s-2004-829151

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One-Pot Clean Synthesis of 1,8-Dioxo-decahydroacridines Catalyzed by p-Dodecylbenezenesulfonic Acid in Aqueous Media

Tong-Shou Jin*, Jian-She Zhang, Tong-Tong Guo, Ai-Qing Wang, Tong-Shuang Li
Department of Chemistry, College of Chemistry and Environmental Science, Hebei University, Baoding 071002, P. R. China
Fax: +86(312)5016914; e-Mail: orgsyn@mail.hbu.edu.cn;

Abstract

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Abstract

Reaction of aromatic aldehyde, 5,5-dimethyl-1,3-cyclohexanedione and p-toluidine in water were successfully carried out in the presence of p-dodecylbenezenesulfonic acid (DBSA) as a Brφnsted acid-surfactant-combined catalyst. This method provides several advantages such as environment friendliness, high yields and simple work-up procedure. In addition, water was chosen as a green solvent.

Key words

decahydroacridine p-dodecylbenezenesulfonic acid - synthesis - aqueous media

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