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DOI: 10.1055/s-2004-830521
© Georg Thieme Verlag KG Stuttgart · New York
Improved Spinal Cord Perfusion during Thoracoabdominal Aortic Repair[1]
Publication History
Received March 3, 2004
Publication Date:
23 March 2005 (online)
Abstract
Objectives: The study's aim is to evaluate whether intraoperative neurophysiological monitoring with transcranial motor-evoked potentials (tcMEP) permits early recognition of neuronal lesions, thus making interventions to prevent irreversible spinal cord damage possible. Material and Methods: TcMEP monitoring was carried out in twelve patients (mean age 60 years) during open surgical thoracoabdominal aortic replacement. Current approaches for corrective, spinal cord-protecting interventions consist of: raising distal perfusion by increasing cardiopulmonary bypass (CPB) flow, catecholamine application, reducing central venous pressure, reimplantation of segmental arteries, and cerebrospinal fluid (CSF) drainage. Results: Nine patients exhibited loss of tcMEP after segmental aorta clamping. In five patients we observed a recovery of tcMEP through counteractive measures. Three patients died intraoperatively, one patient presented with postoperative paraplegia and loss of tcMEP. Conclusion: TcMEP loss is associated with spinal cord ischaemia, causing postoperative paraplegia. TcMEP monitoring is an excellent method to detect spinal cord ischaemia at an early stage.
Key words
Aortic surgery - thoracoabdominal aortic aneurysm - spinal cord perfusion - transcranial motor-evoked potentials (tcMEP)
1 Presented at the Fourth Joint Meeting of The German, Austrian, and Swiss Society for Thoracic and Cardiovascular Surgery, Hamburg, Germany, February 15 - 18, 2004
References
- 1 Carrel A. On the experimental surgery of the thoracic aorta and the heart. Ann Surg. 1910; 52 83-95
- 2 Svensson L G, Rickards E, Coull A, Rogers G, Fimmel C J, Hinder R A. Relationship of spinal cord blood flow to vascular anatomy during thoracic aortic cross-clamping and shunting. J Thorac Cardiovasc Surg. 1986; 91 71-78
- 3 Svensson L G, Crawford E S. Aortic dissection and aortic aneurysm surgery: clinical observations, experimental investigations, and statistical analyses. Part II. Curr Probl Surg. 1992; 29 913-1057
- 4 Wan I Y, Angelini G D, Bryan A J, Ryder I, Underwood M J. Prevention of spinal cord ischaemia during descending thoracic and thoracoabdominal aortic surgery. Eur J Cardiothorac Surg. 2001; 19 203-213
- 5 Svensson L G. New and future approaches for spinal cord protection. Semin Thorac Cardiovasc Surg. 1997; 9 206-221
- 6 MacDonald D B, Janusz M. An approach to intraoperative neurophysiologic monitoring of thoracoabdominal aneurysm surgery. J Clin Neurophysiol. 2002; 19 43-54
- 7 Estrera A L. et al . Descending thoracic aortic aneurysm: surgical approach and treatment using the adjuncts cerebrospinal fluid drainage and distal aortic perfusion. Ann Thorac Surg. 2001; 72 481-486
- 8 Coselli J S. et al . Cerebrospinal fluid drainage reduces paraplegia after thoracoabdominal aortic aneurysm repair: results of a randomized clinical trial. J Vasc Surg. 2002; 35 631-639
- 9 Konrad P E, Tacker W A, Levy W J, Reedy D P, Cook J R, Geddes L A. Motor evoked potentials in the dog: effects of global ischaemia on spinal cord and peripheral nerve signals. Neurosurgery. 1987; 20 117-124
- 10 Reuter D G, Tacker Jr W A, Badylak S F. Voorhees WD 3rd . Correlation of motor-evoked potential response to ischemic spinal cord damage. J Thorac Cardiovasc Surg. 1992; 104 262-272
- 11 Lips J, de Haan P, de Jager S W, Vanicky I, Jacobs M J, Kalkman C J. The role of transcranial motor evoked potentials in predicting neurological and histopathological outcome after experimental spinal cord ischaemia. Anesthesiology. 2002; 97 183-191
- 12 Wan I Y, Angelini G D, Bryan A J, Ryder I, Underwood M J. Prevention of spinal cord ischaemia during descending thoracic and thoracoabdominal aortic surgery. Eur J Cardiothorac Surg. 2001; 19 203-213
- 13 Doyle D J. Spinal cord ischaemia and motor evoked potentials. J Clin Monit. 1990; 6 339-340
- 14 Coselli J S, LeMaire S A, Conklin L D, Koksoy C, Schmittling Z C. Morbidity and mortality after extent II thoracoabdominal aortic aneurysm repair. Ann Thorac Surg. 2002; 73 1107-1115
- 15 LeMaire S A. Miller CC 3rd . A new predictive model for adverse outcomes after elective thoracoabdominal aortic aneurysm repair. Ann Thorac Surg. 2001; 71 1233-1238
- 16 Estrera A L, Miller 3rd C C, Huynh T T, Porat E, Safi H J. Neurologic outcome after thoracic and thoracoabdominal aortic aneurysm repair. Ann Thorac Surg. 2001; 72 1225-1230 1230-1231 (discussion)
1 Presented at the Fourth Joint Meeting of The German, Austrian, and Swiss Society for Thoracic and Cardiovascular Surgery, Hamburg, Germany, February 15 - 18, 2004
MD Ernst Weigang
Department of Cardiovascular Surgery
University Hospital Freiburg, Germany
Hugstetter Straße 55
79106 Freiburg
Germany
Email: weigang@ch11.ukl.uni-freiburg.de