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Synthesis 2004(16): 2760-2765
DOI: 10.1055/s-2004-831164
DOI: 10.1055/s-2004-831164
PSP
© Georg Thieme Verlag Stuttgart · New York
Cyanoacetylation of Indoles, Pyrroles and Aromatic Amines with the Combination Cyanoacetic Acid and Acetic Anhydride
Further Information
Received
1 March 2004
Publication Date:
13 August 2004 (online)
Publication History
Publication Date:
13 August 2004 (online)
Abstract
Cyanoacetic acid was activated with acetic anhydride and when heated this reagent reacted with a variety of both activated and deactivated pyrroles, indoles and aniline derivatives.
Key words
acylations - electrophilic aromatic substitutions - heterocycles - indoles - pyrroles
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References
Slätt, J.; Bergman, J., unpublished results.