Indium(III) Halide Mediated SN2′ Reactions of Substituted Allenols: Synthesis of 2-Halo-1,3-dienes

Yong Seo Cho; Bo Kyung Jun; Ae Nim Pae; Joo Hwan Cha; Hun Yeong Koh; Moon Ho Chang; So-Yeop Han

doi:10.1055/s-2004-831209

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Indium(III) Halide Mediated S_N2′ Reactions of Substituted Allenols: Synthesis of 2-Halo-1,3-dienes

Yong Seo Cho*^a, Bo Kyung Jun^a,b, Ae Nim Pae^a, Joo Hwan Cha^a, Hun Yeong Koh^a, Moon Ho Chang^a, So-Yeop Han^b
^a Biochemicals Research Center, Korea Institute of Science and Technology, P.O. Box 131, Cheongryang, Seoul 130-650, Korea
e-Mail: ys4049@kist.re.kr;
^b Devision of Molecular Life Sciences, Ewha Womans University, 1-1 Daehyun-dong, Seodaemun-gu, Seoul 120-750, Korea

Abstract

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Abstract

Treatment of various substituted allenols with indium(III) halide in benzene gave (Z)- or (E)-2-halo-1,3-dienes in moderate to good yields. In most cases, (2Z)-halo-1,3-dienes were obtained as major products.

Key words

allenol - indium(III) halide - 2-halo-1,3-diene - S_N2′ reaction

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References

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Indium(III) Halide Mediated S N 2′ Reactions of Substituted Allenols: Synthesis of 2-Halo-1,3-dienes

Indium(III) Halide Mediated S_N2′ Reactions of Substituted Allenols: Synthesis of 2-Halo-1,3-dienes