Prospektive Multizenterstudie zur Chirurgie des Magenkarzinoms - Ein Beitrag zur klinischen Versorgungsforschung

L. Meyer; R. Steinert; L. Nowak; K. Gellert; K. Ludwig; D. Saeger; I. Gastinger; H. Lippert

doi:10.1055/s-2005-836491

Zentralblatt für Chirurgie, Table of Contents

Zentralbl Chir 2005; 130(2): 97-105
DOI: 10.1055/s-2005-836491

Originalarbeiten und Übersichten

Prospektive Multizenterstudie zur Chirurgie des Magenkarzinoms - Ein Beitrag zur klinischen Versorgungsforschung

Prospective Multicenter Trial of Gastric Cancer Surgery - A Contribution to Clinical Research on Quality ControlL. Meyer¹ ^, ² , R. Steinert² , L. Nowak¹ , K. Gellert¹ , K. Ludwig¹ , D. Saeger¹ , I. Gastinger¹ ^, ² , H. Lippert¹ ^, ²

¹Ostdeutsche Arbeitsgruppe für Qualitätssicherung und regionale Entwicklung in der Chirurgie e. V.
²Institut für Qualitätssicherung in der operativen Medizin gGmbH an der Otto-von-Guericke-Universität Magdeburg

Abstract

Zusammenfassung

Im Rahmen einer regionalen, prospektiven multizentrischen Beobachtungsstudie (East German Gastric Cancer Study - EGGCS) wurden im Zeitraum vom 1.1. bis 31.12.2002 in 80 ostdeutschen chirurgischen Kliniken 1 139 Patienten mit einem Magenkarzinom erfasst. 1 031 (90,5 %) wurden operiert. Die Resektionsrate betrug 86,4 % (n = 891). Die R0-Resektionsrate (n = 726) lag bei 81,5 %. Der Anteil der Gastrektomien an den radikalen Resektionsverfahren (n = 813) betrug 79,8 % (n = 649). In über 70 % der Eingriffe unter kurativer Intention erfolgte eine D2-Lymphknotendissektion. Eine postoperative Hospitalletalität von 8,3 % wurde registriert. Die Ergebnisse werden vergleichend mit der Deutschen Magenkarzinomstudie (GGCS '92) diskutiert.

Abstract

By the mean of a prospective multicenter observational study (East German Gastric Cancer Study - EGGCS), 1 139 consecutive patients with gastric cancer were enrolled in 80 East German surgical departments from January 1 to December 31, 2002. Out of them, 1,031 (90.5 %) underwent surgical intervention. The resection rate was 86.4 % (n = 891); the R0 resection rate (n = 726) was 81.5 %. Gastrectomy was performed in 79.8 % (n = 649) of subjects with radical resections (n = 813). In approximately 70 % of the interventions with curative intention, lymph node resection of the D2 compartment was carried out. The postoperative hospital mortality was 8.3 %. The results were compared with the data obtained in the German Gastric Cancer Study (GGCS 1992); relevant differences and aspects were discussed.

Schlüsselwörter

Versorgungsforschung - Magenkarzinom - prospektive multizentrische Beobachtungsstudie

Key words

clinical research on quality control - gastric cancer - prospective multicenter observational study

Full Text

References

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Dr. med. Lutz Meyer

Chirurgische Klinik · Carl-Thiem-Klinikum Cottbus

Thiemstr. 111

03048 Cottbus

Phone: +49/3 55/46 23 27

Fax: +49/3 55/46 23 37

Email: L.Meyer@ctk.de