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Endoscopy 2005; 37(5): 460-465
DOI: 10.1055/s-2005-861195
Original Article
© Georg Thieme Verlag KG Stuttgart · New York

Prospective Comparison of Cardiopulmonary Events during Minilaparoscopy and Colonoscopy under Conscious Sedation

U.  Denzer1 , M.  Mollenhauer1 , S.  Kanzler1 , P.  R.  Galle1 , A.  W.  Lohse1
  • 1First Dept. of Medicine, Johannes Gutenberg University, Mainz, Germany
Further Information

Publication History

Submitted 27 June 2004

Accepted after Revision 16 November 2004

Publication Date:
20 April 2005 (online)

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Background and Study Aims: Cardiorespiratory parameters were examined throughout diagnostic minilaparoscopy procedures. The same parameters were analyzed during colonoscopy, and the data were compared.
Patients and Methods: Sixty-five consecutive unselected patients undergoing minilaparoscopy (group 1: ASA I, n = 34; group 2: ASA II/III, n = 31) and 61 consecutive unselected patients undergoing colonoscopy (group 3: ASA I, n = 31; group 4: ASA II/III, n = 30) were included. Oxygen saturation (Sao2), heart rate (HR) and mean arterial pressure (RRm) were measured continuously, and 12-lead electrocardiography (ECG) recordings were made at specific times during each procedure.
Results: Minor differences were observed, particularly after premedication, probably due to different dosage regimens and timing in the two examination techniques. After premedication, testing for differences from baseline values showed a minor decrease in Sao2 and RRm in the minilaparoscopy groups in comparison with the colonoscopy groups (median Sao2, group 1: 99.9 % ± 0 vs. group 3 : 100 % -1, P = 0.0078; median RRm, group 1: 99.5 - 4 mm Hg vs. group 3 : 96 -16 mm Hg, P = 0.046, and median RRm, group 2 : 110 + 1 mm Hg vs. group 4 : 101 -13.5 mm Hg, P = 0.0007). HR increased in minilaparoscopy in comparison with colonoscopy (median HR: group 2 : 77 + 4 beats/min vs. group 4 : 75.5 ± 0 beats/min; P = 0.01). Comparison of defined relevant pathological changes in Sao2, RRm, HR, and ECG showed no significant differences.
Discussion: These data indicate that diagnostic minilaparoscopy under conscious sedation is only associated with limited risk in patients with compensated cardiopulmonary diseases. This is probably due to the low insufflation pressure used.

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U. Denzer, M. D.

First Dept. of Medicine · Johannes Gutenberg University

Langenbeckstrasse 1 · 55131 Mainz · Germany

Fax: +49-6131-175552

Email: denzer@mail.uni-mainz.de