A Convenient and Easy Synthesis of γ-Nitro-α-Acetamido Esters

Roberto Ballini; Cesarino Balsamini; Giuseppe Diamantini; Nicoletta Savoretti

doi:10.1055/s-2005-861873

SHORTPAPER

A Convenient and Easy Synthesis of γ-Nitro-α-Acetamido Esters

Roberto Ballini*^a, Cesarino Balsamini^b, Giuseppe Diamantini^b, Nicoletta Savoretti^b
^a Dipartimento di Scienze Chimiche dell’Università, Via S.Agostino 1, 62032 Camerino (MC), Italy
Fax: +39(0737)402297; e-Mail: roberto.ballini@unicam.it;
^b Istituto di Chimica Farmaceutica-Università degli Studi di Urbino ‘Carlo Bo’, Piazza Rinascimento 6, 61029 Urbino (PU), Italy

Abstract

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Abstract

A microwave-assisted synthesis of γ-nitro acetamido esters, under mild conditions and without solvent, is described. The desired products were obtained via Michael additions from the commercial methyl acetamidoacrylate and nitroalkanes.

Key words

microwave-assisted synthesis - α-amino acids - acetamidoacrylate - nitroalkane - Michael addition

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References

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