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Exp Clin Endocrinol Diabetes 2005; 113(6): 350-353
DOI: 10.1055/s-2005-865599
Case Report

J. A. Barth Verlag in Georg Thieme Verlag KG Stuttgart · New York

Nesidioblastosis - a Rare Cause of Hypoglycaemia in Adults

A. Babińska1 , K. Jaśkiewicz2 , B. Karaszewski1 , 3 , M. Łukiański4 , K. Sworczak1
  • 1Department of Internal Medicine, Endocrinology and Hemostatic Disorders, Medical University of Gdansk, Poland
  • 2Department of Pathology, Medical University of Gdansk, Poland
  • 3Department of Neurology of Adults, Medical University of Gdansk, Poland
  • 4Department of General, Endocrinological, and Transplantation Surgery, Medical University of Gdansk, Poland
Further Information

Publication History

Received: May 12, 2004 First decision: September 20, 2004

Accepted: March 4, 2005

Publication Date:
23 June 2005 (online)

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Abstract

A case of suspected clinically hormonally active insulinoma in a 48-year-old woman is presented. Despite the lack of features, which might correspond to the insulinoma in radiological examinations, the patient was qualified for a distal subtotal pancreatectomy and then, due to persistent hyperinsulinism, for total pancreatectomy. The insulinoma was found neither in a palpable examination of the pancreas nor in the intraoperative ultrasonic examination. In a histopathological examination supplemented with immunohistochemical tests, nesidioblastosis - a rare cause of hypoglycaemia in adults - was diagnosed.

Key words

Nesidioblastosis - hypoglycaemia - hyperinsulinaemia - pancreatectomy - pancreas

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Anna Babinska

Department of Internal Medicine
Endocrinology and Hemostatic Disorders
Medical University of Gdansk

Ul. Debinki 7

80-211 Gdansk

Poland

Phone: + 48583492843

Fax: + 48 5 83 49 28 41

Email: a.mail@wp.pl