Synthesis of 3-Nitropropanol Homologues

James K. Addo; Paul Teesdale-Spittle; John O. Hoberg

doi:10.1055/s-2005-869990

SHORTPAPER

Synthesis of 3-Nitropropanol Homologues

James K. Addo^a, Paul Teesdale-Spittle^b, John O. Hoberg*^c
^a School of Chemical and Physical Sciences, Victoria University of Wellington, Wellington, New Zealand
^b School of Biological Sciences, Victoria University of Wellington, Wellington, New Zealand
^c Department of Chemistry, University of Wyoming, Laramie, WY 82071, USA
Fax: +1(307)7662807; e-Mail: hoberg@uwyo.edu;

Abstract

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Abstract

Several high yielding routes to oxygenated nitropropanes have been developed that include a palladium catalyzed nitro allylation of allylic carbonates, nitration of brominated compounds and a nitro aldol condensation/hydrogenation sequence.

Key words

nitroaldol - 3-nitropropanol - 3-nitropropanal - 3-nitropropanoic acid - ethyl glyoxylate

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