Endoscopy 2005; 37(10): 1027-1029
DOI: 10.1055/s-2005-870218
Case Report
© Georg Thieme Verlag KG Stuttgart · New York

Polyethylene Glycol-Electrolyte Lavage Solution Causes Reversible Mucosal Elevation Surrounding a Minute Depressed-Type Rectal Cancer

C.  Yamamoto1 , K.  Aoyagi1 , K.  Maeda1 , K.  Eguchi1 , H.  Nishimura1 , S.  Sakisaka1
  • 1Third Department of Medicine, Fukuoka University School of Medicine, Fukuoka, Japan
Further Information

Publication History

Submitted 26 November 2004

Accepted after Revision 23 February 2005

Publication Date:
27 September 2005 (online)

A 52-year-old man underwent colonoscopy following preparation with polyethylene glycol-electrolyte lavage solution (PEG-ELS), which revealed a flat elevated lesion with an irregular depression in the rectum. Three days after this colonoscopy, flexible sigmoidoscopy was performed after preparation with a glycerin enema and this examination demonstrated an irregular depressed lesion which was not associated with a surrounding elevated lesion. Seven days after the flexible sigmoidoscopy, colonoscopy following preparation with PEG-ELS revealed an elevated lesion surrounding the depressed lesion. Fourteen days after this second colonoscopy, flexible sigmoidoscopy following preparation with a glycerin enema showed a depressed lesion and an endoscopic mucosal resection was performed: histological examination revealed the tumor to be a well-differentiated adenocarcinoma. We report a patient in whom PEG-ELS led to the reversible appearance of an elevated lesion around a minute rectal cancer and believe that this reactive elevated lesion might prove to be a useful clue in the detection of minute rectal cancers.

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C. Yamamoto, M. D.

Third Department of Medicine · Fukuoka University School of Medicine

7-45-1 Nanakuma · Johnan-ku · Fukuoka 814-0180 · Japan

Fax: +81-92-874-2663

Email: cyama@fukuoka-u.ac.jp