Hepatocellular Carcinoma in Type 1 Gaucher Disease: A Case Report with Review of the Literature

Ruliang Xu; Pramod Mistry; Gregg Mckenna; Sukru Emre; Maria Isabel Fiel; Thomas Schiano; Moueen Bu-Ghanim; Gabriel Levi

doi:10.1055/s-2005-871201

Seminars in Liver Disease, Table of Contents

Semin Liver Dis 2005; 25(2): 226-229
DOI: 10.1055/s-2005-871201

DIAGNOSTIC PROBLEMS IN HEPATOLOGY

Hepatocellular Carcinoma in Type 1 Gaucher Disease: A Case Report with Review of the Literature

Ruliang Xu¹ , Pramod Mistry³ , Gregg Mckenna² , Sukru Emre² , Thomas Schiano² , Moueen Bu-Ghanim¹ , Gabriel Levi¹ , Maria Isabel Fiel¹

¹Lillian and Henry M. Stratton- Hans Popper Department of Pathology, Division of Hepatopathology, New York, New York
²Recanati-Miller Transplantation Institute, Mount Sinai Medical Center, New York, New York
³Department of Internal Medicine, Section of Digestive Diseases, Yale University School of Medicine, New Haven, Connecticut

Abstract

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References

REFERENCES

1 Shiran A, Brenner B, Laor A, Tatarsky I. Increased risk of cancer in patients with Gaucher disease. Cancer. 1993; 72 219-224
2 James S P, Stromeyer F W, Chang C, Barranger J A. Liver abnormalities in patients with Gaucher's disease. Gastroenterology. 1981; 80 126-133
3 Lachmann R H, Wight D G, Lomas D J et al.. Massive hepatic fibrosis in Gaucher's disease: clinico-pathological and radiological features. QJM. 2000; 93 237-244
4 Breiden-Langen C M, Buchsel R, Brambs H J, Oehlert M, Matern S. Coincidence of Gaucher disease with primary hepatocellular carcinoma. Leber Magen Darm. 1991; 21 126 129-130
5 Erjavec Z, Hollak C E, de Vries E G. Hepatocellular carcinoma in a patient with Gaucher disease on enzyme supplementation therapy. Ann Oncol. 1999; 10 243
6 Bohm P, Kunz W, Horny H P, Einsele H. Adult Gaucher disease in association with primary malignant bone tumors. Cancer. 2001; 91 457-462
7 Chang-Lo M, Yam L T, Rubenstone A I, Schwartz S O. Gaucher's disease associated with chronic lymphocytic leukaemia, gout and carcinoma. J Pathol. 1975; 116 203-207
8 Davis M, Dorfman J. Gaucher's disease associated with a cerebral astrocytoma. A case report involving an adult. Am Pract Dig Treat. 1961; 12 673-677
9 Gupta M K, Levin M, Aguilera N S, Pastores G M. Littoral cell angioma of the spleen in a patient with Gaucher disease. Am J Hematol. 2001; 68 61-62
10 Kenan S, Abdelwahab I F, Hermann G, Klein M, Pastores G. Osteoblastoma of the humerus associated with type-I Gaucher's disease. A case report. J Bone Joint Surg Br. 1996; 78 702-705
11 Kojiro M, Kage M, Abe H, Imamura M, Shiraishi K, Mizoguchi M. Association of dysgerminoma and Gaucher's disease. Cancer. 1983; 51 712-715
12 Lyons J C, Scheithauer B W, Ginsburg W W. Gaucher's disease and glioblastoma multiforme in two siblings: a clinicopathologic study. J Neuropathol Exp Neurol. 1982; 41 45-53
13 Pins M R, Mankin H J, Xavier R J, Rosenthal D I, Dickersin G R, Rosenberg A E. Malignant epithelioid hemangioendothelioma of the tibia associated with a bone infarct in a patient who had Gaucher disease. A case report. J Bone Joint Surg Am. 1995; 77 777-781
14 Tsung S H, Cotes E. Coexistence of bronchogenic carcinoma and Gaucher disease. Arch Pathol Lab Med. 1977; 101 56
15 Watanabe M, Yanagisawa M, Sonobe S, Matsumoto J, Miura H. An adult form of Gaucher's disease with a huge tumour formation of the right tibia. Int Orthop. 1984; 8 195-202
16 Bertram H C, Eldibany M, Padgett J, Dragon L H. Splenic lymphoma arising in a patient with Gaucher disease. A case report and review of the literature. Arch Pathol Lab Med. 2003; 127 242-245
17 Gal R, Gukovsky-Oren S, Floru S, Djaldetti M, Kessler E. Sequential appearance of breast carcinoma, multiple myeloma and Gaucher's disease. Haematologica. 1988; 73 63-65

Ruliang XuM.D. Ph.D.

The Lillian and Henry M. Stratton- Hans Popper Department of Pathology, Mount Sinai School of Medicine

One Gustave L. Levy Place

New York, NY 10029

Email: ruliang.xu@msnyuhealth.org