Preparation and Synthetic Use of Polymer-Supported Acetoacetate Reagent

Takeshi Hirai; Hideo Togo

doi:10.1055/s-2005-872142

PAPER

Preparation and Synthetic Use of Polymer-Supported Acetoacetate Reagent

Takeshi Hirai^a, Hideo Togo*^a,b
^a Graduate School of Science and Technology, Chiba University, Yayoi-cho 1-33, Inage-ku 263-8522, Chiba, Japan
^b Department of Chemistry, Faculty of Science, Chiba University, Yayoi-cho 1-33, Inage-ku 263-8522, Chiba, Japan
Fax: +81(43)2902874; e-Mail: togo@faculty.chiba-u.jp;

Abstract

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Abstract

Coumarin synthesis using polymer-supported acetoacetate reagent was carried out to produce various coumarin derivatives in excellent yield and purity with a facile work-up process. It was found that the polymer reagent could be recycled without any diminishment of the yield and purity.

Key words

polymer-supported acetoacetate - coumarin - Knoevenagel condensation - von Pechmann reaction - green chemistry

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