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Planta Med 2005; 71(12): 1176-1178
DOI: 10.1055/s-2005-873139
DOI: 10.1055/s-2005-873139
Letter
© Georg Thieme Verlag KG Stuttgart · New York
Cytotoxic Activity of Some Natural and Synthetic Sesquiterpene Lactones
Further Information
Publication History
Received: April 13, 2005
Accepted: May 27, 2005
Publication Date:
10 November 2005 (online)


Abstract
Several natural and synthetic sesquiterpene lactones with different skeletons were tested and found to be active against nine cancer cell lines. Elemane (4), heliangolane (5) and their hydroxy analogues 9 and 10, all containing an α,β-unsaturated aldehyde substituent, were the most potent compounds.