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Planta Med 2005; 71(12): 1176-1178
DOI: 10.1055/s-2005-873139
DOI: 10.1055/s-2005-873139
Letter
© Georg Thieme Verlag KG Stuttgart · New York
Cytotoxic Activity of Some Natural and Synthetic Sesquiterpene Lactones
Further Information
Publication History
Received: April 13, 2005
Accepted: May 27, 2005
Publication Date:
10 November 2005 (online)
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Abstract
Several natural and synthetic sesquiterpene lactones with different skeletons were tested and found to be active against nine cancer cell lines. Elemane (4), heliangolane (5) and their hydroxy analogues 9 and 10, all containing an α,β-unsaturated aldehyde substituent, were the most potent compounds.
References
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Prof. Maurizio Bruno
Dipartimento di Chimica Organica ”E. Paternò”
Università di Palermo
Viale delle Scienze
Parco d’Orleans II
90128 Palermo
Italy
Phone: +39-(0)91-596-905
Fax: +39-(0)91-596-825
Email: bruno@dicpm.unipa.it