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DOI: 10.1055/s-2005-921151
Biliary Tract Obstruction Due to Sarcoidosis
G. C. Sotiropoulos, M. D.
Department of General Surgery and Transplantation
University Hospital Essen
Hufelandstraße 55
45122 Essen
Germany
Fax: +49-201-7231113
eMail: georgios.sotiropoulos@uni-essen.de
Publikationsverlauf
Submitted
Accepted after revision
Publikationsdatum:
18. Mai 2006 (online)
Figure 1 A 31-year-old woman was admitted to our hospital with a new episode of cholangitis, in the course of primary sclerosing cholangitis. Endoscopic and radiological evaluation suggested a bile duct carcinoma. a Diagnostic endoscopic retrograde cholangiography (ERC) showed typical findings of primary sclerosing cholangitis, as well as a suspicious lesion in the liver hilum. b Transverse computed tomography (CT) demonstrated a tumor lesion in the liver hilum. c Positron emission tomography (PET) images showed pathologically increased glucose metabolism in the upper abdomen. d This mapped accurately to the tumor lesion shown in b, when fused PET and CT data were assessed. Exploratory laparotomy followed. Enlarged lymph nodes were identified in the liver hilum, that were causing dilatation of the common bile duct. Lymphadenectomy in the liver hilum and bile duct resection were performed, followed by hepaticojejunostomy with Roux-en-Y anastomosis. Surprisingly, histological investigation proved hepatobiliary sarcoidosis.
Figure 2 a On histological examination, the lymph nodes showed sarcoidal, noncaseating epitheloid granulomas. b Liver biopsy showed cholestasis, duct proliferation and granuloma formation, typical findings of granulomatous hepatitis. The masked clinical presentation of this case of Klatskin tumor-mimicking sarcoidosis reminds us of this rare cause of biliary tract obstruction.
Endoscopy_UCTN_Code_CCL_1AZ_2AZ
G. C. Sotiropoulos, M. D.
Department of General Surgery and Transplantation
University Hospital Essen
Hufelandstraße 55
45122 Essen
Germany
Fax: +49-201-7231113
eMail: georgios.sotiropoulos@uni-essen.de
G. C. Sotiropoulos, M. D.
Department of General Surgery and Transplantation
University Hospital Essen
Hufelandstraße 55
45122 Essen
Germany
Fax: +49-201-7231113
eMail: georgios.sotiropoulos@uni-essen.de
Figure 1 A 31-year-old woman was admitted to our hospital with a new episode of cholangitis, in the course of primary sclerosing cholangitis. Endoscopic and radiological evaluation suggested a bile duct carcinoma. a Diagnostic endoscopic retrograde cholangiography (ERC) showed typical findings of primary sclerosing cholangitis, as well as a suspicious lesion in the liver hilum. b Transverse computed tomography (CT) demonstrated a tumor lesion in the liver hilum. c Positron emission tomography (PET) images showed pathologically increased glucose metabolism in the upper abdomen. d This mapped accurately to the tumor lesion shown in b, when fused PET and CT data were assessed. Exploratory laparotomy followed. Enlarged lymph nodes were identified in the liver hilum, that were causing dilatation of the common bile duct. Lymphadenectomy in the liver hilum and bile duct resection were performed, followed by hepaticojejunostomy with Roux-en-Y anastomosis. Surprisingly, histological investigation proved hepatobiliary sarcoidosis.
Figure 2 a On histological examination, the lymph nodes showed sarcoidal, noncaseating epitheloid granulomas. b Liver biopsy showed cholestasis, duct proliferation and granuloma formation, typical findings of granulomatous hepatitis. The masked clinical presentation of this case of Klatskin tumor-mimicking sarcoidosis reminds us of this rare cause of biliary tract obstruction.