Abstract
Background: The aim of the present study was to examine the influence of the number of sternal fixation wires used on deep sternal wound infection rate and to analyze any possible interaction between this and local collagen-gentamicin prophylaxis evaluated in a previous trial. Methods: The number of sternal fixation wires in all patients from one of two participating centers was counted. The patients were categorized according to six or fewer (standard technique, ST group) vs. seven or more wires (extra wires, XW group). Results: The incidence of deep sternal wound infection was 4.2 % in the ST group and 0.4 % in the XW group (p = 0.001). An analysis of the effect of local gentamicin, excluding the ST group from the analysis, showed an approximately 70 % reduction in sternal wound infection for all depths. Conclusion: This study supports the theory that additional fixation wires at the lower sternum actually reduce the incidence of deep wound infections. We suggest that a rigid sternal fixation is required to achieve the full benefit of local collagen-gentamicin prophylaxis.
Key words
Cardiovascular surgery - coronary bypass surgery - heart valve surgery
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Örjan Friberg
Department of Cardiothoracic Surgery and Anesthesiology
Örebro University Hospital
70185 Örebro
Sweden
Phone: + 46 1 96 02 10 00
Fax: + 46 1 96 11 39 43
Email: orjan.friberg@orebroll.se
