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Synthesis 2006(8): 1343-1350
DOI: 10.1055/s-2006-926414
DOI: 10.1055/s-2006-926414
PAPER
© Georg Thieme Verlag Stuttgart · New York
Suzuki Coupling at the 2-Position of Densely Functionalized Pyrimidones
Further Information
Received
23 November 2005
Publication Date:
28 March 2006 (online)
Publication History
Publication Date:
28 March 2006 (online)
Abstract
A variety of ethyl 1-substituted 2-aryl-5-ethoxy-6-oxo-1,6-dihydropyrimidine-4-carboxylates were synthesized by efficient thermal or microwave-promoted Suzuki coupling of 2-chloro-N1-substituted precursors.
Key words
antiviral agents - pyrimidones - cross-coupling
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