Two New Phthalides from Ligusticum chuanxiong

Abstract

Two new phthalide dimers, namely chuanxiongnolide A (1) and chuanxiongnolide B (2), along with eleven known phthalides and derivatives (3 - 13), were isolated from the roots of Ligusticum chuanxiong Hort. (Umbelliferae). The chemical structures of the new compounds were established by HR-ESI-MS, 1D- and 2D-NMR spectroscopic analysis, whilst the relative stereochemistry of 1 was confirmed by X-ray crystallographic data.

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