Abstract
Surgery for temporal lobe epilepsy refractory to medical treatment is a promising treatment option. After a short overview of historical developments in this field, we describe the present practice of presurgical evaluation and resection strategies as practiced at our institution and review the corresponding publications from other centers. We will be trying to outline major future developments for the surgical therapy of temporal lobe epilepsy based on present trends.
Zusammenfassung
Die operative Behandlung der medikamentös therapierefraktären Temporallappenepilepsie ist eine viel versprechende Behandlungsoption. Nach einem kurzen Überblick über die historische Entwicklung der Epilepsiechirurgie beschreiben wir die gegenwärtige Praxis der prächirurgischen Evaluation und der Resektionsstrategie, so wie sie an unserem Zentrum derzeit praktiziert werden. Darüberhinaus werden relevante Arbeiten anderer Zentren vorgestellt und diskutiert, um aus den gegenwärtigen Trends richtungsweisende zukünftige Entwicklungen der chirurgischen Behandlung bei Temporallappenepilepsie abzuleiten.
Key words
epilepsy surgery - epilepsy - temporal lobe
Schlüsselwörter
Epilepsiechirurgie - Epilepsie - Temporallappen
References
-
1
Altshuler L, Rausch R, Delrahim S, Kay J, Crandall P.
Temporal lobe epilepsy, temporal lobectomy, and major depression.
J Neuropsychiatry Clin Neurosci.
1999;
11
436-443
-
2
Armon C, Radtke R A, Friedman A H, Dawson D V.
Predictors of outcome of epilepsy surgery: multivariate analysis with validation.
Epilepsia.
1996;
37
814-821
-
3
Arruda F, Cendes F, Andermann F, Dubeau F, Villemure J G, Jones-Gotman M, Poulin N, Arnold D L, Olivier A.
Mesial atrophy and outcome after amygdalohippocampectomy or temporal lobe removal.
Ann Neurol.
1996;
40
446-450
-
4
Assaf B A, Karkar K M, Laxer K D, Garcia P A, Austin E J, Barbaro N M, Aminoff M J.
Magnetoencephalography source localization and surgical outcome in temporal lobe epilepsy.
Clin Neurophysiol.
2004;
115
2066-2076
-
5
Awad I A, Katz A, Hahn J F, Kong A K, Ahl J, Luders H.
Extent of resection in temporal lobectomy for epilepsy. I. Interobserver analysis and correlation with seizure outcome.
Epilepsia.
1989;
30
756-762
-
6
Awad I A, Nayel M H, Luders H.
Second operation after the failure of previous resection for epilepsy.
Neurosurgery.
1991;
28
510-518
-
7
Aydemir N, Ozkara C, Canbeyli R, Tekcan A.
Changes in quality of life and self-perspective related to surgery in patients with temporal lobe epilepsy.
Epilepsy Behav.
2004;
5
735-742
-
8
Bailey P, Gibbs F.
The surgical treatment of psychomotor epilepsy.
JAMA.
1951;
145
365-370
-
9
Behrens E, Schramm J, Zentner J, Konig R.
Surgical and neurological complications in a series of 708 epilepsy surgery procedures.
Neurosurgery.
1997;
41
1-9
-
10
Behrens E, Zentner J, Van Roost D, Hufnagel A, Elger C E, Schramm J.
Subdural and depth electrodes in the presurgical evaluation of epilepsy.
Acta Neurochir (Wien).
1994;
128
84-87
-
11
Bengzon A R, Rasmussen T, Gloor P, Dussault J, Stephens M.
Prognostic factors in the surgical treatment of temporal lobe epileptics.
Neurology.
1968;
18
717-731
-
12
Berg A T, Vickrey B G, Langfitt J T, Sperling M R, Walczak T S, Shinnar S, Bazil C W, Pacia S V, Spencer S S.
The multicenter study of epilepsy surgery: recruitment and selection for surgery.
Epilepsia.
2003;
44
1425-1433
-
13
Berger H.
Über das Elektrenkephalogramm des Menschen.
Arch Psychiat Nervenkr.
1929;
87
527-570
-
14
Berkovic S F, McIntosh A M, Kalnins R M, Jackson G D, Fabinyi G C, Brazenor G A, Bladin P F, Hopper J L.
Preoperative MRI predicts outcome of temporal lobectomy: an actuarial analysis.
Neurology.
1995;
45
1358-1363
-
15
Bertram E H, Williamson J M, Cornett J F, Spradlin S, Chen Z F.
Design and construction of a long-term continuous video-EEG monitoring unit for simultaneous recording of multiple small animals.
Brain Res Brain ResProtoc.
1997;
2
85-97
-
16
Bladin P F.
Psychosocial difficulties and outcome after temporal lobectomy.
Epilepsia.
1992;
33
898-907
-
17
Blatt D R, Roper S N, Friedman W A.
Invasive monitoring of limbic epilepsy using stereotactic depth and subdural strip electrodes: surgical technique.
Surg Neurol.
1997;
48
74-79
-
18
Bonilha L, Kobayashi E, Mattos J P, Honorato D C, Li L M, Cendes F.
Value of extent of hippocampal resection in the surgical treatment of temporal lobe epilepsy.
Arq Neuropsiquiatr.
2004;
62
15-20
-
19
Carne R P, O'Brien T J, Kilpatrick C J, MacGregor L R, Hicks R J, Murphy M A, Bowden S C, Kaye A H, Cook M J.
MRI-negative PET-positive temporal lobe epilepsy: a distinct surgically remediable syndrome.
Brain.
2004;
127
2276-2285
-
20
Cascino G D.
Video-EEG monitoring in adults.
Epilepsia.
2002;
43
80-93
-
21
Cascino G D.
Surgical treatment for epilepsy.
Epilepsy Res.
2004;
60
179-186
-
22
Cascino G D, Jack Jr C R, Parisi J E, Marsh W R, Kelly P J, Sharbrough F W, Hirschorn K A, Trenerry M R.
MRI in the presurgical evaluation of patients with frontal lobe epilepsy and children with temporal lobe epilepsy: pathologic correlation and prognostic importance.
Epilepsy Res.
1992;
11
51-59
-
23
Cascino G D, Jack Jr C R, Parisi J E, Sharbrough F W, Hirschorn K A, Meyer F B, Marsh W R, O'Brien P C.
Magnetic resonance imaging-based volume studies in temporal lobe epilepsy: pathological correlations.
Ann Neurol.
1991;
30
31-36
-
24
Cascino G D, Trenerry M R, Sharbrough F W, So E L, Marsh W R, Strelow D C.
Depth electrode studies in temporal lobe epilepsy: relation to quantitative magnetic resonance imaging and operative outcome.
Epilepsia.
1995;
36
230-235
-
25
Cascino G D, Trenerry M R, So E L, Sharbrough F W, Shin C, Lagerlund T D, Zupanc M L, Jack Jr C R.
Routine EEG and temporal lobe epilepsy: relation to long-term EEG monitoring, quantitative MRI, and operative outcome.
Epilepsia.
1996;
37
651-656
-
26
Cendes F, Cook M J, Watson C, Andermann F, Fish D R, Shorvon S D, Bergin P, Free S, Dubeau F, Arnold D L.
Frequency and characteristics of dual pathology in patients with lesional epilepsy.
Neurology.
1995;
45
2058-2064
-
27
Cendes F, Leproux F, Melanson D, Ethier R, Evans A, Peters T, Andermann F.
MRI of amygdala and hippocampus in temporal lobe epilepsy.
J Comput Assist Tomogr.
1993;
17
206-210
-
28
Chovaz C J, McLachlan R S, Derry P A, Cummings A L.
Psychosocial function following temporal lobectomy: influence of seizure control and learned helplessness.
Seizure.
1994;
3
171-176
-
29
Clusmann H, Kral T, Fackeldey E, Blumcke I, Helmstaedter C, Oertzen J von, Urbach H, Schramm J.
Lesional mesial temporal lobe epilepsy and limited resections - prognostic factors and outcome.
J Neurol Neurosurg Psychiatry.
2004;
75
1589-1596
-
30
Clusmann H, Kral T, Gleissner U, Sassen R, Urbach H, Blumcke I, Bogucki J, Schramm J.
Analysis of different types of resection for pediatric patients with temporal lobe epilepsy.
Neurosurgery.
2004;
54
1-13
-
31
Clusmann H, Kral T, Marin G, Van Roost D, Swamy K, Schramm J.
Characterization of hemorrhagic complications after surgery for temporal lobe epilepsy.
Zentralbl Neurochir.
2004;
65
128-134
-
32
Clusmann H, Schramm J, Kral T, Helmstaedter C, Ostertun B, Fimmers R, Haun D, Elger C E.
Prognostic factors and outcome after different types of resection for temporal lobe epilepsy.
J Neurosurg.
2002;
97
1131-1141
-
33
Cohen-Gadol A A, Britton J W, Wetjen N M, Marsh W R, Meyer F B, Raffel C.
Neurostimulation therapy for epilepsy: current modalities and future directions.
Mayo Clin Proc.
2003;
78
238-248
-
34
Daumas-Duport C, Scheithauer B W, Chodkiewicz J P, Laws Jr E R, Vedrenne C.
Dysembryoplastic neuroepithelial tumor: a surgically curable tumor of young patients with intractable partial seizures. Report of thirty-nine cases.
Neurosurgery.
1988;
23
545-556
-
35
Duncan R, Patterson J, Roberts R, Hadley D M, Bone I.
Ictal/postictal SPECT in the pre-surgical localisation of complex partial seizures.
J Neurol Neurosurg Psychiatry.
1993;
56
141-148
-
36
Egan R A, Shults W T, So N, Burchiel K, Kellogg J X, Salinsky M.
Visual field deficits in conventional anterior temporal lobectomy versus amygdalohippocampectomy.
Neurology.
2000;
55
1818-1822
-
37
Elger C E, Grunwald T, Lehnertz K, Kutas M, Helmstaedter C, Brockhaus A, Van Roost D, Heinze H J.
Human temporal lobe potentials in verbal learning and memory processes.
Neuropsychologia.
1997;
35
657-667
-
38 Elger C E, Hufnagel A, Schramm J. Epilepsy surgery protocol University Hospital, Bonn, Germany. In: Luders HO (ed). Epilepsy Surgery. Raven Press, New York 1992; 783-784
-
39
Elwes R D, Dunn G, Binnie C D, Polkey C E.
Outcome following resective surgery for temporal lobe epilepsy: a prospective follow up study of 102 consecutive cases.
J Neurol Neurosurg Psychiatry.
1991;
54
949-952
-
40 Engel Jr J, Van Ness P, Rasmussen T B, Ojemann L M. Outcome with respect to epileptic seizures. In: Engel Jr J (ed). Surgical Treatment of the Epilepsies. 2nd ed. Raven Press, New York 1993; 609-621
-
41
Engel Jr J.
Multimodal approaches in the evaluation of epilepsy patients for surgery.
Electroencephalogr Clin Neurophysiol Suppl.
1999;
50
40-52
-
42
Engel Jr J.
A greater role for surgical treatment of epilepsy: Why and when?.
Epilepsy Curr.
2003;
3
37-40
-
43 Engel Jr J. Surgical Treatment of the Epilepsies. Raven Press, New York 1993
-
44
Falconer M A.
Discussion on the surgery of temporal lobe epilepsy: surgical and poathological aspects.
Proceedings of the Royal Society of Medicine.
1953;
46
971-974
-
45
Falconer M A.
The significance of mesial temporal sclerosis (Ammon's horn sclerosis) in epilepsy.
Guys Hosp Rep.
1968;
117
1-12
-
46
Falconer M A, Taylor D C.
Surgical treatment of drug-resistant epilepsy due to mesial temporal sclerosis. Etiology and significance.
Arch Neurol.
1968;
19
353-361
-
47
Fernandez G, de Greiff A, Oertzen J von, Reuber M, Lun S, Klaver P, Ruhlmann J, Reul J, Elger C E.
Language mapping in less than 15 minutes: real-time functional MRI during routine clinical investigation.
Neuroimage.
2001;
14
585-594
-
48
Fernandez G, Hufnagel A, Van Roost D, Helmstaedter C, Wolf H K, Zentner J, Schramm J, Elger C E.
Safety of intrahippocampal depth electrodes for presurgical evaluation of patients with intractable epilepsy.
Epilepsia.
1997;
38
922-929
-
49
Fischer M J, Scheler G, Stefan H.
Utilization of magnetoencephalography results to obtain favourable outcomes in epilepsy surgery.
Brain.
2005;
128
153-157
-
50
Foerster O.
Pathogenese und chirurgische Behandlung der Epilepsie.
Zentralbl Chir.
1925;
52
531-549
-
51
Foldvary N, Nashold B, Mascha E, Thompson E A, Lee N, McNamara J O, Lewis D V, Luther J S, Friedman A H, Radtke R A.
Seizure outcome after temporal lobectomy for temporal lobe epilepsy: a Kaplan-Meier survival analysis.
Neurology.
2000;
54
630-634
-
52
Germano I M, Poulin N, Olivier A.
Reoperation for recurrent temporal lobe epilepsy.
J Neurosurg.
1994;
81
31-36
-
53
Gil-Fernandez J J.
Analysis of surgical blood loss and number of blood transfusions after temporal lobe resection performed in adults with epilepsy receiving valproate (VPA) in the immediate preoperative period.
Epilepsia.
1997;
38
1257-1258
-
54
Gilliam F.
The impact of epilepsy on subjective health status.
Curr Neurol Neurosci Rep.
2003;
3
357-362
-
55
Gilliam F, Faught E, Martin R, Bowling S, Bilir E, Thomas J, Morawetz R, Kuzniecky R.
Predictive value of MRI-identified mesial temporal sclerosis for surgical outcome in temporal lobe epilepsy: an intent-to-treat analysis.
Epilepsia.
2000;
41
963-966
-
56
Gleissner U, Helmstaedter C, Elger C E.
Right hippocampal contribution to visual memory: a presurgical and postsurgical study in patients with temporal lobe epilepsy.
J Neurol Neurosurg Psychiatry.
1998;
65
665-669
-
57
Gleissner U, Helmstaedter C, Schramm J, Elger C E.
Memory outcome after selective amygdalohippocampectomy: a study in 140 patients with temporal lobe epilepsy.
Epilepsia.
2002;
43
87-95
-
58
Gleissner U, Helmstaedter C, Schramm J, Elger C E.
Memory outcome after selective amygdalohippocampectomy in patients with temporal lobe epilepsy: one-year follow-up.
Epilepsia.
2004;
45
960-962
-
59
Gleissner U, Sassen R, Lendt M, Clusmann H, Elger C E, Helmstaedter C.
Pre- and postoperative verbal memory in pediatric patients with temporal lobe epilepsy.
Epilepsy Res.
2002;
51
287-296
-
60 Goldensohn E. Historical perspectives. In: Engel Jr J, Pedley TA (eds). Epilepsy: A comprehensive Textbook. Lippincott-Raven Publishers, Philadelphia 1997; 15-39
-
61
Goldstein L H, Polkey C E.
Behavioural memory after temporal lobectomy or amygdalo-hippocampectomy.
Br J Clin Psychol.
1992;
31
75-81
-
62
Goldstein L H, Polkey C E.
Short-term cognitive changes after unilateral temporal lobectomy or unilateral amygdalo-hippocampectomy for the relief of temporal lobe epilepsy.
J Neurol Neurosurg Psychiatry.
1993;
56
135-140
-
63
Grunwald T, Elger C E, Lehnertz K, Van Roost D, Heinze H J.
Alterations of intrahippocampal cognitive potentials in temporal lobe epilepsy.
Electroencephalogr Clin Neurophysiol.
1995;
95
53-62
-
64
Grunwald T, Lehnertz K, Pezer N, Kurthen M, Van Roost D, Schramm J, Elger C E.
Prediction of postoperative seizure control by hippocampal event-related potentials.
Epilepsia.
1999;
40
303-306
-
65
Guldvog B, Loyning Y, Hauglie-Hanssen E, Flood S, Bjornaes H.
Predictive factors for success in surgical treatment for partial epilepsy: a multivariate analysis.
Epilepsia.
1994;
35
566-578
-
66
Hamer H M, Najm I, Mohamed A, Wyllie E.
Interictal epileptiform discharges in temporal lobe epilepsy due to hippocampal sclerosis versus medial temporal lobe tumors.
Epilepsia.
1999;
40
1261-1268
-
67
Hellstrand E, Abraham-Fuchs K, Jernberg B, Kihlstrom L, Knutsson E, Lindquist C, Schneider S, Wirth A.
MEG localization of interictal epileptic focal activity and concomitant stereotactic radiosurgery. A non-invasive approach for patients with focal epilepsy.
Physiol Meas.
1993;
14
131-136
-
68
Helmstaedter C.
Neuropsychological aspects of epilepsy surgery.
Epilepsy Behav.
2004;
5 (Suppl 1)
S45-S55
-
69
Helmstaedter C, Elger C E.
Cognitive consequences of two-thirds anterior temporal lobectomy on verbal memory in 144 patients: a three-month follow-up study.
Epilepsia.
1996;
37
171-180
-
70
Helmstaedter C, Elger C E, Hufnagel A, Zentner J, Schramm J.
Different effects of left anterior temporal lobectomy, selective amygdalohippocampectomy, and temporal cortical lesionectomy on verbal learning, memory, and recognition.
J Epilepsy.
1996;
9
39-45
-
71
Helmstaedter C, Grunwald T, Lehnertz K, Gleissner U, Elger C E.
Differential involvement of left temporolateral and temporomesial structures in verbal declarative learning and memory: evidence from temporal lobe epilepsy.
Brain Cogn.
1997;
35
110-131
-
72 Helmstaedter C, Lendt M, Lux S. VMLT Verbaler Lern- und Merkfähigkeitstest. Beltz Test GmbH, Göttingen 2001
-
73
Helmstaedter C, Pohl C, Hufnagel A, Elger C E.
Visual learning deficits in nonresected patients with right temporal lobe epilepsy.
Cortex.
1991;
27
547-555
-
74
Helmstaedter C, Van Roost D, Clusmann H, Urbach H, Elger C E, Schramm J.
Collateral brain damage, a potential source of cognitive impairment after selective surgery for control of mesial temporal lobe epilepsy.
J Neurol Neurosurg Psychiatry.
2004;
75
323-326
-
75
Hennessy M J, Elwes R D, Binnie C D, Polkey C E.
Failed surgery for epilepsy: A study of persistence and recurrence of seizures following temporal resection.
Brain.
2000;
123
2445-2466
-
76
Hennessy M J, Elwes R D, Honavar M, Rabe-Hesketh S, Binnie C D, Polkey C E.
Predictors of outcome and pathological considerations in the surgical treatment of intractable epilepsy associated with temporal lobe lesions.
J Neurol Neurosurg Psychiatry.
2001;
70
450-458
-
77
Hennessy M J, Elwes R D, Rabe-Hesketh S, Binnie C D, Polkey C E.
Prognostic factors in the surgical treatment of medically intractable epilepsy associated with mesial temporal sclerosis.
Acta Neurol Scand.
2001;
103
344-350
-
78
Hermann B P, Wyler A R, Bush A J, Tabatabai F R.
Differential effects of left and right anterior temporal lobectomy on verbal learning and memory performance.
Epilepsia.
1992;
33
289-297
-
79
Ho S S, Berkovic S F, Berlangieri S U, Newton M R, Egan G F, Tochon-Danguy H J, McKay W J.
Comparison of ictal SPECT and interictal PET in the presurgical evaluation of temporal lobe epilepsy.
Ann Neurol.
1995;
37
738-745
-
80
Ho S S, Berkovic S F, McKay W J, Kalnins R M, Bladin P F.
Temporal lobe epilepsy subtypes: differential patterns of cerebral perfusion on ictal SPECT.
Epilepsia.
1996;
37
788-795
-
81
Ho S S, Newton M R, McIntosh A M, Kalnins R M, Fabinyi G C, Brazenor G A, McKay W J, Bladin P F, Berkovic S F.
Perfusion patterns during temporal lobe seizures: relationship to surgical outcome.
Brain.
1997;
120
1921-1928
-
82
Holmes M D, Born D E, Kutsy R L, Wilensky A J, Ojemann G A, Ojemann L M.
Outcome after surgery in patients with refractory temporal lobe epilepsy and normal MRI.
Seizure.
2000;
9
407-411
-
83
Honnegger J, Zentner J, Spreer J, Carmona H, Schulze-Bonhage A.
Cerebellar hemorrhage arising postoperatively as a complication of supratentorial surgery: a retrospective study.
J Neurosurg.
2002;
96
248-254
-
84
Hufnagel A, Dumpelmann M, Zentner J, Schijns O, Elger C E.
Clinical relevance of quantified intracranial interictal spike activity in presurgical evaluation of epilepsy.
Epilepsia.
2000;
41
467-478
-
85
Iannelli A, Guzzetta F, Battaglia D, Iuvone L, Di Rocco C.
Surgical treatment of temporal tumors associated with epilepsy in children.
Pediatr Neurosurg.
2000;
32
248-254
-
86
Ivnik R J, Sharbrough F W, Laws E R.
Effects of anterior temporal lobectomy on cognitive function.
J Clin Psychol.
1987;
43
128-137
-
87
Jack C R, Sharbrough F W, Twomey C K, Cascino G D, Hirschorn K A, Marsh W R, Zinsmeister A R, Scheithauer B.
Temporal lobe seizures: lateralization with MR volume measurements of the hippocampal formation.
Radiology.
1990;
175
423-429
-
88
Janszky J, Jokeit H, Kontopoulou K, Mertens M, Ebner A, Pohlmann-Eden B, Woermann F G.
Functional MRI predicts memory performance after right mesiotemporal epilepsy surgery.
Epilepsia.
2005;
46
244-250
-
89
Janszky J, Ollech I, Jokeit H, Kontopoulou K, Mertens M, Pohlmann-Eden B, Ebner A, Woermann F G.
Epileptic activity influences the lateralization of mesiotemporal fMRI activity.
Neurology.
2004;
63
1813-1817
-
90 Jasper H H. Electrencephalography. In: Penfield W, Erickson T (eds). Epilepsy and Cerebral Localization. Charles C. Thomas, Springfield, Ill. 1941; 380-454
-
91
Jeong S W, Lee S K, Kim K K, Kim H, Kim J Y, Chung C K.
Prognostic factors in anterior temporal lobe resections for mesial temporal lobe epilepsy: multivariate analysis.
Epilepsia.
1999;
40
1735-1739
-
92
Jokeit H, Okujava M, Woermann F G.
Memory fMRI lateralizes temporal lobe epilepsy.
Neurology.
2001;
57
1786-1793
-
93
Jones-Gotman M, Harnadek M C, Kubu C S.
Neuropsychological assessment for temporal lobe epilepsy surgery.
Can J Neurol Sci.
2000;
27 (Suppl 1)
39-43
-
94
Kaiboriboon K, Lowe V J, Chantarujikapong S I, Hogan R E.
The usefulness of subtraction ictal SPECT coregistered to MRI in single- and dual-headed SPECT cameras in partial epilepsy.
Epilepsia.
2002;
43
408-414
-
95
Kalfas I H, Little J R.
Postoperative hemorrhage: a survey of 4 992 intracranial procedures.
Neurosurgery.
1988;
23
343-347
-
96
Kanner A M, Kaydanova Y, de Toledo-Morrell L, Morrell F, Smith M C, Bergen D, Pierre-Louis S J, Ristanovic R.
Tailored anterior temporal lobectomy. Relation between extent of resection of mesial structures and postsurgical seizure outcome.
Arch Neurol.
1995;
52
173-178
-
97
Katz A, Awad I A, Kong A K, Chelune G J, Naugle R I, Wyllie E, Beauchamp G, Luders H.
Extent of resection in temporal lobectomy for epilepsy. II. Memory changes and neurologic complications.
Epilepsia.
1989;
30
763-771
-
98
Killgore W D, Glosser G, Casasanto D J, French J A, Alsop D C, Detre J A.
Functional MRI and the Wada test provide complementary information for predicting post-operative seizure control.
Seizure.
1999;
8
450-455
-
99
Kim H, Yi S, Son E I, Kim J.
Lateralization of epileptic foci by neuropsychological testing in mesial temporal lobe epilepsy.
Neuropsychology.
2004;
18
141-151
-
100
Knowlton R C.
Magnetoencephalography: clinical application in epilepsy.
Curr Neurol Neurosci Rep.
2003;
3
341-348
-
101
Knowlton R C, Laxer K D, Ende G, Hawkins R A, Wong S T, Matson G B, Rowley H A, Fein G, Weiner M W.
Presurgical multimodality neuroimaging in electroencephalographic lateralized temporal lobe epilepsy.
Ann Neurol.
1997;
42
829-837
-
102
Krakow K, Lemieux L, Messina D, Scott C A, Symms M R, Duncan J S, Fish D R.
Spatio-temporal imaging of focal interictal epileptiform activity using EEG-triggered functional MRI.
Epileptic Disord.
2001;
3
67-74
-
103
Kral T, Clusmann H, Blumcke I, Fimmers R, Ostertun B, Kurthen M, Schramm J.
Outcome of epilepsy surgery in focal cortical dysplasia.
J Neurol Neurosurg Psychiatry.
2003;
74
183-188
-
104
Kral T, Clusmann H, Urbach H, Schramm J, Elger C E, Kurthen M, Grunwald T.
Preoperative Evaluation for epilepsy surgery (Bonn Algorithm).
Zentralbl Neurochir.
2002;
63
106-110
-
105
Kurthen M, Linke D B, Elger C E, Schramm J.
Linguistic perseveration in dominant-side intracarotid amobarbital tests.
Cortex.
1992;
28
209-219
-
106 Lamberti G, Weidlich S. DCS - A visual learning and memory test for neuropsychological assessment. Hogrefe & Huber Publishers, Seattle, Toronto, Bern, Göttingen 1999
-
107
Lamusuo S, Jutila L, Ylinen A, Kalviainen R, Mervaala E, Haaparanta M, Jaaskelainen S, Partanen K, Vapalahti M, Rinne J.
[18F]FDG-PET reveals temporal hypometabolism in patients with temporal lobe epilepsy even when quantitative MRI and histopathological analysis show only mild hippocampal damage.
Arch Neurol.
2001;
58
933-939
-
108
Lee S K, Lee S H, Kim S K, Lee D S, Kim H.
The clinical usefulness of ictal SPECT in temporal lobe epilepsy: the lateralization of seizure focus and correlation with EEG.
Epilepsia.
2000;
41
955-962
-
109
Lee W S, Lee J K, Lee S A, Kang J K, Ko T S.
Complications and results of subdural grid electrode implantation in epilepsy surgery.
Surg Neurol.
2000;
54
346-351
-
110
Lemieux L.
Electroencephalography-correlated functional MR imaging studies of epileptic activity.
Neuroimaging Clin N Am.
2004;
14
487-506
-
111
Lemieux L, Salek-Haddadi A, Josephs O, Allen P, Toms N, Scott C, Krakow K, Turner R, Fish D R.
Event-related fMRI with simultaneous and continuous EEG: description of the method and initial case report.
Neuroimage.
2001;
14
780-787
-
112
Liston A D, Salek-Haddadi A, Kiebel S J, Hamandi K, Turner R, Lemieux L.
The MR detection of neuronal depolarization during 3-Hz spike-and-wave complexes in generalized epilepsy.
Magn Reson Imaging.
2004;
22
1441-1444
-
113
Litt B, Lehnertz K.
Seizure prediction and the preseizure period.
Curr Opin Neurol.
2002;
15
173-177
-
114
Loring D W, Meador K J, Lee G P.
Determinants of quality of life in epilepsy.
Epilepsy Behav.
2004;
5
976-980
-
115
Luders H, Awad I, Burgess R, Wyllie E, Van Ness P.
Subdural electrodes in the presurgical evaluation for surgery of epilepsy.
Epilepsy Res Suppl.
1992;
5
147-156
-
116
Lutz M T, Clusmann H, Elger C E, Schramm J, Helmstaedter C.
Neuropsychological outcome after selective amygdalohippocampectomy with transsylvian versus transcortical approach: a randomized prospective clinical trial of surgery for temporal lobe epilepsy.
Epilepsia.
2004;
45
809-816
-
117
Luyken C, Blumcke I, Fimmers R, Urbach H, Elger C E, Wiestler O D, Schramm J.
The spectrum of long-term epilepsy-associated tumors: long-term seizure and tumor outcome and neurosurgical aspects.
Epilepsia.
2003;
44
822-830
-
118
Luyken C, Blumcke I, Fimmers R, Urbach H, Wiestler O D, Schramm J.
Supratentorial gangliogliomas: histopathologic grading and tumor recurrence in 184 patients with a median follow-up of 8 years.
Cancer.
2004;
101
146-155
-
119
Mace C J, Trimble M R.
Psychosis following temporal lobe surgery: a report of six cases.
J Neurol Neurosurg Psychiatry.
1991;
54
639-644
-
120
Macewen W.
Intra-cranial lesions - illustrating some points in connexion with the localization of cerebral affection and the advantages of antiseptiv trephining.
Lancet.
1881;
2
581
-
121
Manno E M, Sperling M R, Ding X, Jaggi J, Alavi A, O'Connor M J, Reivich M.
Predictors of outcome after anterior temporal lobectomy: positron emission tomography.
Neurology.
1994;
44
2331-2336
-
122
Mathern G W, Babb T L, Leite J P, Pretorius K, Yeoman K M, Kuhlman P A.
The pathogenic and progressive features of chronic human hippocampal epilepsy.
Epilepsy Res.
1996;
26
151-161
-
123
McDonald C R, Norman M A, Tecoma E, Alksne J, Iragui V.
Neuropsychological change following gamma knife surgery in patients with left temporal lobe epilepsy: a review of three cases.
Epilepsy Behav.
2004;
5
949-957
-
124
McKhann G M, Schoenfeld-McNeill J, Born D E, Haglund M M, Ojemann G A.
Intraoperative hippocampal electrocorticography to predict the extent of hippocampal resection in temporal lobe epilepsy surgery.
J Neurosurg.
2000;
93
44-52
-
125
Mohamed A, Wyllie E, Ruggieri P, Kotagal P, Babb T, Hilbig A, Wylie C, Ying Z, Staugaitis S, Najm I, Bulacio J, Foldvary N, Luders H, Bingaman W.
Temporal lobe epilepsy due to hippocampal sclerosis in pediatric candidates for epilepsy surgery.
Neurology.
2001;
56
1643-1649
-
126
Morris H H, Matkovic Z, Estes M L, Prayson R A, Comair Y G, Turnbull J, Najm I, Kotagal P, Wyllie E.
Ganglioglioma and intractable epilepsy: clinical and neurophysiologic features and predictors of outcome after surgery.
Epilepsia.
1998;
39
307-313
-
127
Nayel M H, Awad I A, Luders H.
Extent of mesiobasal resection determines outcome after temporal lobectomy for intractable complex partial seizures.
Neurosurgery.
1991;
29
55-60
-
128 Niemeyer P. The transventricular amygdala-hippocampectomy in temporal lobe epilepsy. In: Baldwin M, Bailey P (eds). Temporal Lobe Epilepsy. Charles C. Thomas, Springfield, IL. 1958; 461-482
-
129
O'Brien T J, O'Connor M K, Mullan B P, Brinkmann B H, Hanson D, Jack C R, So E L.
Subtraction ictal SPET co-registered to MRI in partial epilepsy: description and technical validation of the method with phantom and patient studies.
Nucl Med Commun.
1998;
19
31-45
-
130
O'Brien T J, So E L, Mullan B P, Hauser M F, Brinkmann B H, Bohnen N I, Hanson D, Cascino G D, Jack Jr C R, Sharbrough F W.
Subtraction ictal SPECT co-registered to MRI improves clinical usefulness of SPECT in localizing the surgical seizure focus.
Neurology.
1998;
50
445-454
-
131
Olivier A.
Relevance of removal of limbic structures in surgery for temporal lobe epilepsy.
Can J Neurol Sci.
1991;
18
628-635
-
132
Ozkara C, Ozyurt E, Hanoglu L, Eskazan E, Dervent A, Kocer N, Ozmen M, Onat F, Oz B, Kuday C.
Surgical outcome of epilepsy patients evaluated with a noninvasive protocol.
Epilepsia.
2000;
41
41-44
-
133
Palmer J D, Sparrow O C, Iannotti F.
Postoperative hematoma: a 5-year survey and identification of avoidable risk factors.
Neurosurgery.
1994;
35
1061-1064
-
134 Pilcher W, Roberts D, Flanigin H F, Crandal P H, Wieser H G, Ojemann G A, Peacock W J. Complications of epilepsy surgery. In: Engel J (ed). Surgical Treatment of the Epilepsies. 2nd ed. Raven Press, New York 1993; 565-581
-
135 Polkey C. Complications of epilepsy surgery. In: Shorvon SD, Dreifuss F, Fish D, Thomas D (eds). The Treatment of Epilepsy. Blackwell Science, Oxford 1996; 780-793
-
136
Polkey C E.
Clinical outcome of epilepsy surgery.
Curr Opin Neurol.
2004;
17
173-178
-
137
Radhakrishnan K, So E L, Silbert P L, Jack Jr C R, Cascino G D, Sharbrough F W, O'Brien P C.
Predictors of outcome of anterior temporal lobectomy for intractable epilepsy: a multivariate study.
Neurology.
1998;
51
465-471
-
138
Radtke R A, Hanson M W, Hoffman J M, Crain B J, Walczak T S, Lewis D V, Beam C, Coleman R E, Friedman A H.
Temporal lobe hypometabolism on PET: predictor of seizure control after temporal lobectomy.
Neurology.
1993;
43
1088-1092
-
139 Rasmussen T, Jasper H H. Temporal lobe epilepsy: Indications for operation and surgical technique. In: Baldwin M, Bailey P (eds). Temporal Lobe Epilepsy. Charles C. Thomas, Springfield, IL. 1958; 440-460
-
140
Raymond A A, Fish D R, Sisodiya S M, Alsanjari N, Stevens J M, Shorvon S D.
Abnormalities of gyration, heterotopias, tuberous sclerosis, focal cortical dysplasia, microdysgenesis, dysembryoplastic neuroepithelial tumour and dysgenesis of the archicortex in epilepsy. Clinical, EEG and neuroimaging features in 100 adult patients.
Brain.
1995;
118
629-660
-
141
Raymond A A, Fish D R, Stevens J M, Cook M J, Sisodiya S M, Shorvon S D.
Association of hippocampal sclerosis with cortical dysgenesis in patients with epilepsy.
Neurology.
1994;
44
1841-1845
-
142
Raymond A A, Halpin S F, Alsanjari N, Cook M J, Kitchen N D, Fish D R, Stevens J M, Harding B N, Scaravilli F, Kendall B.
Dysembryoplastic neuroepithelial tumor. Features in 16 patients.
Brain.
1994;
117
461-475
-
143
Regis J, Bartolomei F, Rey M, Genton P, Dravet C, Semah F, Gastaut J L, Chauvel P, Peragut J C.
Gamma knife surgery for mesial temporal lobe epilepsy.
Epilepsia.
1999;
40
1551-1556
-
144
Regis J, Rey M, Bartolomei F, Vladyka V, Liscak R, Schrottner O, Pendl G.
Gamma knife surgery in mesial temporal lobe epilepsy: a prospective multicenter study.
Epilepsia.
2004;
45
504-515
-
145
Renowden S A, Matkovic Z, Adams C B, Carpenter K, Oxbury S, Molyneux A J, Anslow P, Oxbury J.
Selective amygdalohippocampectomy for hippocampal sclerosis: postoperative MR appearance.
Am J Neuroradiol.
1995;
16
1855-1861
-
146
Reuber M, Andersen B, Elger C E, Helmstaedter C.
Depression and anxiety before and after temporal lobe epilepsy surgery.
Seizure.
2004;
13
129-135
-
147
Reuber M, Kurthen M, Fernandez G, Schramm J, Elger C E.
Epilepsy surgery in patients with additional psychogenic seizures.
Arch Neurol.
2002;
59
82-86
-
148
Richardson M P, Strange B A, Thompson P J, Baxendale S A, Duncan J S, Dolan R J.
Pre-operative verbal memory fMRI predicts post-operative memory decline after left temporal lobe resection.
Brain.
2004;
127
2419-2426
-
149
Salanova V, Markand O, Worth R.
Temporal lobe epilepsy surgery: outcome, complications, and late mortality rate in 215 patients.
Epilepsia.
2002;
43
170-174
-
150
Salanova V, Markand O, Worth R, Garg B, Patel H, Asconape J, Park H M, Hutchins G D, Smith R, Azzarelli B.
Presurgical evaluation and surgical outcome of temporal lobe epilepsy.
Pediatr Neurol.
1999;
20
179-184
-
151
Scherrmann J, Hoppe C, Kral T, Schramm J, Elger C E.
Vagus nerve stimulation: clinical experience in a large patient series.
J Clin Neurophysiol.
2001;
18
408-414
-
152
Schramm J, Aliashkevich A F, Grunwald T.
Multiple subpial transections: outcome and complications in 20 patients who did not undergo resection.
J Neurosurg.
2002;
97
39-47
-
153
Schramm J, Kral T, Grunwald T, Blumcke I.
Surgical treatment for neocortical temporal lobe epilepsy: clinical and surgical aspects and seizure outcome.
J Neurosurg.
2001;
94
33-42
-
154
Scott C A, Fish D R, Smith S J, Free S L, Stevens J M, Thompson P J, Duncan J S, Shorvon S D, Harkness W F.
Presurgical evaluation of patients with epilepsy and normal MRI: role of scalp video-EEG telemetry.
J Neurol Neurosurg Psychiatry.
1999;
66
69-71
-
155
Seidenberg M, Hermann B, Wyler A R, Davies K, Dohan Jr F C, Leveroni C.
Neuropsychological outcome following anterior temporal lobectomy in patients with and without the syndrome of mesial temporal lobe epilepsy.
Neuropsychology.
1998;
12
303-316
-
156
Siegel A M, Jobst B C, Thadani V M, Rhodes C H, Lewis P J, Roberts D W, Williamson P D.
Medically intractable, localization-related epilepsy with normal MRI: presurgical evaluation and surgical outcome in 43 patients.
Epilepsia.
2001;
42
883-888
-
157
Silbergeld D L.
Extent of medial temporal resection on outcome from anterior temporal lobectomy: a randomized prospective study.
Neurosurgery.
1997;
41
327-328
-
158
Spencer S S.
The relative contributions of MRI, SPECT, and PET imaging in epilepsy.
Epilepsia.
1994;
35
72-89
-
159
Spencer S S, Berg A T, Vickrey B G, Sperling M R, Bazil C W, Shinnar S, Langfitt J T, Walczak T S, Pacia S V, Ebrahimi N, Frobish D.
Initial outcomes in the Multicenter Study of Epilepsy Surgery.
Neurology.
2003;
61
1680-1685
-
160
Spencer S S, Spencer D D, Williamson P D, Mattson R.
Combined depth and subdural electrode investigation in uncontrolled epilepsy.
Neurology.
1990;
40
74-79
-
161
Spencer S S, Spencer D D, Williamson P D, Mattson R H.
The localizing value of depth electroencephalography in 32 patients with refractory epilepsy.
Ann Neurol.
1982;
12
248-253
-
162
Spencer S S, Theodore W H, Berkovic S F.
Clinical applications: MRI, SPECT, and PET.
Magn Reson Imaging.
1995;
13
1119-1124
-
163
Sperling M R, Saykin A J, Glosser G, Moran M, French J A, Brooks M, O'Connor M J.
Predictors of outcome after anterior temporal lobectomy: the intracarotid amobarbital test.
Neurology.
1994;
44
2325-2330
-
164
Srikijvilaikul T, Najm I, Foldvary-Schaefer N, Lineweaver T, Suh J H, Bingaman W E.
Failure of gamma knife radiosurgery for mesial temporal lobe epilepsy: report of five cases.
Neurosurgery.
2004;
54
1395-1402
, ; discussion 1402-1394
-
165
Stefan H, Hummel C, Scheler G, Genow A, Druschky K, Tilz C, Kaltenhauser M, Hopfengartner R, Buchfelder M, Romstock J.
Magnetic brain source imaging of focal epileptic activity: a synopsis of 455 cases.
Brain.
2003;
126
2396-2405
-
166
Stefan H, Pauli E, Eberhard F, Ugrinovich R, Buchfelder M.
[“Tailoring” resections in drug refractory temporal lobe epilepsy].
Nervenarzt.
1996;
67
306-310
-
167
Sutherland G R, Kaibara T, Louw D F.
Intraoperative MR at 1.5 Tesla - experience and future directions.
Acta Neurochir Suppl.
2003;
85
21-28
-
168
Sylaja P N, Radhakrishnan K, Kesavadas C, Sarma P S.
Seizure outcome after anterior temporal lobectomy and its predictors in patients with apparent temporal lobe epilepsy and normal MRI.
Epilepsia.
2004;
45
803-808
-
169
Szaflarski J P, Holland S K, Schmithorst V J, Dunn R S, Privitera M D.
High-resolution functional MRI at 3T in healthy and epilepsy subjects: hippocampal activation with picture encoding task.
Epilepsy Behav.
2004;
5
244-252
-
170
Toczek M T, Morrell M J, Silverberg G A, Lowe G M.
Cerebellar hemorrhage complicating temporal lobectomy. Report of four cases.
J Neurosurg.
1996;
85
718-722
-
171
Tonini C, Beghi E, Berg A T, Bogliun G, Giordano L, Newton R W, Tetto A, Vitelli E, Vitezic D, Wiebe S.
Predictors of epilepsy surgery outcome: a meta-analysis.
Epilepsy Res.
2004;
62
75-87
-
172
Urbach H, Hattingen J, Oertzen J von, Luyken C, Clusmann H, Kral T, Kurthen M, Schramm J, Blumcke I, Schild H H.
MR imaging in the presurgical workup of patients with drug-resistant epilepsy.
Am J Neuroradiol.
2004;
25
919-926
-
173
Urbach H, Kurthen M, Klemm E, Grunwald T, Van Roost D, Linke D B, Biersack H J, Schramm J, Elger C E.
Amobarbital effects on the posterior hippocampus during the intracarotid amobarbital test.
Neurology.
1999;
52
1596-1602
-
174
Urbach H, Oertzen J von, Klemm E, Koenig R, Linke D B, Kurthen M, Schramm J, Elger C E.
Selective middle cerebral artery Wada tests as a part of presurgical evaluation in patients with drug-resistant epilepsies.
Epilepsia.
2002;
43
1217-1223
-
175
Van Roost D, Schaller C, Meyer B, Schramm J.
Can neuronavigation contribute to standardization of selective amygdalohippocampectomy?.
Stereotact Funct Neurosurg.
1997;
69
239-242
-
176
Van Roost D, Solymosi L, Schramm J, van Oosterwyck B, Elger C E.
Depth electrode implantation in the length axis of the hippocampus for the presurgical evaluation of medial temporal lobe epilepsy: a computed tomography-based stereotactic insertion technique and its accuracy.
Neurosurgery.
1998;
43
819-826
-
177
Vickrey B G, Hays R D, Engel Jr J, Spritzer K, Rogers W H, Rausch R, Graber J, Brook R H.
Outcome assessment for epilepsy surgery: the impact of measuring health-related quality of life.
Ann Neurol.
1995;
37
158-166
-
178
von Oertzen J, Urbach H, Blumcke I, Reuber M, Traber F, Peveling T, Menzel C, Elger C E.
Time-efficient T2 relaxometry of the entire hippocampus is feasible in temporal lobe epilepsy.
Neurology.
2002;
58
257-264
-
179
von Oertzen J, Urbach H, Jungbluth S, Kurthen M, Reuber M, Fernandez G, Elger C E.
Standard magnetic resonance imaging is inadequate for patients with refractory focal epilepsy.
J Neurol Neurosurg Psychiatry.
2002;
73
643-647
-
180
Vonck K, Boon P, Goossens L, Dedeurwaerdere S, Claeys P, Gossiaux F, Van Hese P, De Smedt T, Raedt R, Achten E, Deblaere K, Thieleman A, Vandemaele P, Thiery E, Vingerhoets G, Miatton M, Caemaert J, Van Roost D, Baert E, Michielsen G, Dewaele F, Van Laere K, Thadani V, Robertson D, Williamson P.
Neurostimulation for refractory epilepsy.
Acta Neurol Belg.
2003;
103
213-217
-
181
Wellmer J, Oertzen J von, Schaller C, Urbach H, Konig R, Widman G, Van Roost D, Elger C E.
Digital photography and 3D MRI-based multimodal imaging for individualized planning of resective neocortical epilepsy surgery.
Epilepsia.
2002;
43
1543-1550
-
182
Westerveld M, Sass K J, Chelune G J, Hermann B P, Barr W B, Loring D W, Strauss E, Trenerry M R, Perrine K, Spencer D D.
Temporal lobectomy in children: cognitive outcome.
J Neurosurg.
2000;
92
24-30
-
183
Wiebe S, Blume W T, Girvin J P, Eliasziw M.
A randomized, controlled trial of surgery for temporal-lobe epilepsy.
N Engl J Med.
2001;
345
311-318
-
184
Wieser H G.
Future aspects of epilepsy research.
Acta Neurochir Suppl.
2002;
84
1-16
-
185
Wieser H G, Blume W T, Fish D, Goldensohn E, Hufnagel A, King D, Sperling M R, Luders H, Pedley T A.
ILAE Commission Report. Proposal for a new classification of outcome with respect to epileptic seizures following epilepsy surgery.
Epilepsia.
2001;
42
282-286
-
186
Wieser H G, Ortega M, Friedman A, Yonekawa Y.
Long-term seizure outcomes following amygdalohippocampectomy.
J Neurosurg.
2003;
98
751-763
-
187
Wieser H G, Yasargil M G.
Selective amygdalohippocampectomy as a surgical treatment of mesiobasal limbic epilepsy.
Surg Neurol.
1982;
17
445-457
-
188
Woermann F G, Jokeit H, Luerding R, Freitag H, Schulz R, Guertler S, Okujava M, Wolf P, Tuxhorn I, Ebner A.
Language lateralization by Wada test and fMRI in 100 patients with epilepsy.
Neurology.
2003;
61
699-701
-
189
Wyler A R, Hermann B P, Richey E T.
Results of reoperation for failed epilepsy surgery.
J Neurosurg.
1989;
71
815-819
-
190
Wyler A R, Hermann B P, Somes G.
Extent of medial temporal resection on outcome from anterior temporal lobectomy: a randomized prospective study.
Neurosurgery.
1995;
37
982-990
-
191
Yasargil M G.
Intracranial microsurgery.
Clin Neurosurg.
1970;
17
250-256
-
192
Yasargil M G, Teddy P J, Roth P.
Selective amygdalo-hippocampectomy. Operative anatomy and surgical technique.
Adv Tech Stand Neurosurg.
1985;
12
93-123
-
193
Yasargil M G, Vise W M, Bader D C.
Technical adjuncts in neurosurgery.
Surg Neurol.
1977;
8
331-336
-
194
Zabramski J M, Wascher T M, Spetzler R F, Johnson B, Golfinos J, Drayer B P, Brown B, Rigamonti D, Brown G.
The natural history of familial cavernous malformations: results of an ongoing study.
J Neurosurg.
1994;
80
422-432
-
195
Zentner J, Hufnagel A, Wolf H K, Ostertun B, Behrens E, Campos M G, Elger C E, Wiestler O D, Schramm J.
Surgical treatment of neoplasms associated with medically intractable epilepsy.
Neurosurgery.
1997;
41
378-386
Priv.-Doz. Dr. med. H. Clusmann
Klinik für Neurochirurgie · Universitätsklinikum Bonn
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Germany
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