Pharmacopsychiatry 2006; 39(3): 114
DOI: 10.1055/s-2006-946609
Letter
© Georg Thieme Verlag KG Stuttgart · New York

Dramatic Remission of Treatment-resistant Depression after the Cessation of Tricyclic Antidepressants

A Case ReportK. Yoshida1 , Y. Sugawara2 , H. Higuchi3
  • 1Department of Psychiatry, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi 466-8550, Japan
  • 2Department of Psychiatry, Akita University School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan
  • 3Omagari City Hospital, 210 Aza-sekihigashi, Iida, Omagari 014-0067, Japan.
Weitere Informationen

Publikationsverlauf

Received: 15.11.2005

Accepted: 12.1.2006

Publikationsdatum:
23. Mai 2006 (online)

Preview

Recently, tricyclic antidepressants (TCAs) have been used mainly for treatment-resistant depression (TRD) because of their significant side effects [5]. We report a patient whose prolonged depressive symptoms dramatically improved after the cessation of TCAs. TCAs may cause deterioration of depressive symptoms due to their neurotoxicity.

References

Keizo Yoshida, M.D., Ph. D.

Department of Psychiatry

Nagoya University Graduate School of Medicine

65 Tsurumai-cho

Showa-ku

Nagoya

Aichi 466-8550

Japan

Telefon: +81 52 744 2283

Fax: +81 52 744 2293

eMail: cxw01076@nifty.com