Thorac Cardiovasc Surg 2007; 55(7): 424-427
DOI: 10.1055/s-2007-965377
Original Cardiovascular

© Georg Thieme Verlag KG Stuttgart · New York

Left Ostial Stenosis Surgical Angioplasty

K. G. Perreas1 , S. Dimitriou1 , E. Ntalarizou1 , P. Kalogris1 , G. Amanatidis1 , M. Khoury1 , G. Karatassakis1 , A. Michalis1
  • 1Department of B Cardiac Surgery, Onassis Cardiac Centre, Athens, Greece
Further Information

Publication History

received March 26, 2007

Publication Date:
28 September 2007 (online)

Abstract

Background: Left main coronary stenosis, including ostial lesions, is conventionally treated by coronary bypass surgery. This approach, however, restores a less physiological retrograde perfusion to part of the myocardium and may contribute to a competition of flows in non-occluded coronaries. Direct surgical reconstruction of the LMCA has been described and theoretically avoids these potential drawbacks.

Methods: From May 1995 until December 2005, 25 patients with ostial left main stenosis underwent surgical angioplasty in our unit. Patients were all followed up clinically and with transesophageal echocardiography. Results: Mean age of the patients was 59.7 years (range, 33 - 73 years). The male to female ratio was 14 : 11. The left main coronary stem was approached anteriorly in all patients. The onlay patch consisted of saphenous vein and was extended across the aortotomy suture line. There were no early deaths or perioperative myocardial infarctions. All patients underwent follow-up clinical examination and transesophageal (TOE) echocardiography as well as other investigations when required. TOE demonstrated a wide open left main coronary artery normal flow pattern, and no aneurysmal dilatation or calcification of the onlay patch in 24 patients. After a mean follow-up of 8 years, the all-cause survival was 88 %, while event-free survival was 80 % with 21 pts remaining in CCS I. Conclusion: Surgical reconstruction of the LMCA is a safe and effective treatment for left main stenosis. Re-institution of normal blood flow through the left main coronary artery possibly confers advantages over bypass surgery.

References

  • 1 Thompson R. Isolated coronary ostial stenosis in women.  J Am Coll Cardiol. 1986;  7 997-1003
  • 2 Cipriano P R, Silverman J F, Perloth M G, Griepp R G, Wexler L. Coronary arterial narrowing in Takayasu's aortitis.  Am J Cardiol. 1977;  39 744-750
  • 3 Gaudiani V A, Siegel S B, McIntosh-Vellin N L. Left main coronary artery reconstruction after radiation therapy.  Ann Thorac Surg. 1994;  58 567-569
  • 4 Frater R WN, Jordan A. Syphilitic coronary ostial stenosis.  Ann Thorac Surg. 1968;  6 463-467
  • 5 Loop F D, Lytle B W, Cosgrove D M. et al . Atherosclerosis of the left main coronary artery: 5 year results of surgical treatment.  Am J Cardiol. 1979;  44 195-201
  • 6 Barner H B, Naunheim K S, Kanter K R. et al . Coronary ostial stenosis.  Eur J Cardiothorac Surg. 1988;  2 106-112
  • 7 DeMots H, Rosch J, McAnulty J H, Rahimtoola S H. Left main coronary artery disease. Rahimtoola SH Coronary Bypass Surgery. Philadelphia; F. A. Davis Company 1977: 201
  • 8 Ridley P D, Wisheart J D. Coronary ostial reconstruction.  Ann Thorac Surg. 1996;  62 293-295
  • 9 Effler D B, Sones F M, Favaloro R, Groves L K. Coronary endarterectomy with patch graft reconstruction: clinical experience with 34 cases.  Ann Surg. 1965;  162 590-601
  • 10 Hitchcock J F, Robles de Medina E O, Jambroes G. Angioplasty of the left main coronary artery for isolated left main coronary artery disease.  J Thorac Cardiovasc Surg. 1983;  85 880-884
  • 11 Dion R, Elias B, El Khoury, Noirhomme P, Verhlest R, Hanet C. Surgical angioplasty of the left main coronary artery.  Eur J Cardiothorac Surg. 1997;  11 857-864
  • 12 Brener S J, Lytle B W, Casserly I P. et al . Propensity analysis of long-term survival after surgical or percutaneous revascularization in patients with multivessel coronary artery disease of the left main coronary artery.  Eur J Cardiothorac Surg. 1997;  11 857-864
  • 13 Dihmis W C, Hutter J A. Ostioplasty for isolated coronary artery stenosis.  J Thorac Cardiovasc Surg. 1995;  109 600
  • 14 Jegaden O, Eker A, Durand de Gevigney G, Montagna P, Ossette J, Mikaeloff P. Surgical angioplasty of the coronary trunks: an alternative to bypass techniques.  Coron Artery Dis. 1994;  5 519-524
  • 15 Chen Q, Khaddour A, Tang A, Livesey S. Surgical ostioplasty for isolated ostial stenosis of the left main stem coronary artery.  Tex Heart Inst J. 2001;  28 193-195
  • 16 Suma H. Left main coronary artery reconstruction by patch angioplasty (letter).  Eur J Cardiothorac Surg. 1995;  9 537
  • 17 Nagy Z L, Szokol M, Peterffy A. Direct ostioplasty of the main coronary artery using the right internal thoracic artery as patch material.  Eur J Cardiothorac Surg. 2001;  20 1233-1234
  • 18 Liska J, Jonsson A, Lockowandt U, Herzfeld I, Gelinder S, Franco-Cereceda A. Arterial patch angioplasty for reconstruction of proximal coronary artery stenosis.  Ann Thorac Surg. 1999;  68 2185-2190
  • 19 Malyshev M, Gladyshev I, Safuanov A, Siniukov D, Borovikov D, Rostovykh N. Surgical angioplasty of the left main coronary artery and/or proximal segment of the right coronary artery by pulmonary autograft patch.  Euro J Cardiothorac Surg. 2004;  25 21-25
  • 20 Moro H, Hayashi J, Nakayama T. Patch angioplasty of left main coronary artery.  Ann Thorac Surg. 1999;  67 1209-1218

Dr. A. Michalis

Department of B Cardiac Surgery
Onassis Cardiac Centre

Sygrou 356

17674 Athens

Greece

Phone: + 30 69 72 92 32 23

Fax: + 30 2 10 94 93 93 31

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