A Rapid and Efficient Synthesis of Benzimidazoles Using Hypervalent Iodine as Oxidant

Li-Hua Du; Yan-Guang Wang

doi:10.1055/s-2007-965922

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Synthesis 2007(5): 675-678
DOI: 10.1055/s-2007-965922

PAPER

A Rapid and Efficient Synthesis of Benzimidazoles Using Hypervalent Iodine as Oxidant

Li-Hua Du, Yan-Guang Wang*
Department of Chemistry, Zhejiang University, Hangzhou 310027, P. R. of China
Fax: +86(571)87951512; e-Mail: orgwyg@zju.edu.cn;

Further Information

Publication History

Received 16 October 2006
Publication Date:
08 February 2007 (online)

Abstract
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Abstract

Various 2-arylbenzimidazoles were synthesized from phenylenediamines and aldehydes via a one-step process using hypervalent iodine as an oxidant. The salient features of this method include mild conditions, short reaction times (3-5 min), high yields, and simple procedure.

Key words

benzimidazoles - iodobenzene diacetate (IBD) - oxidations - o-phenylenediamines

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