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Synthesis 2007(8): 1165-1168
DOI: 10.1055/s-2007-965984
DOI: 10.1055/s-2007-965984
PAPER
© Georg Thieme Verlag Stuttgart · New York
An Efficient Method for the α-Acetoxylation of Ketones
Further Information
Received
29 November 2006
Publication Date:
12 March 2007 (online)
Publication History
Publication Date:
12 March 2007 (online)
Abstract
α-Acetoxylation of ketones catalyzed by iodobenzene using 30% aqueous hydrogen peroxide and acetic anhydride as the oxidant is an effective and economical method for the preparation of α-acetoxy ketones. The reaction gave the products in good yields without the addition of acetic acid and water.
Key words
acetoxylation - iodobenzene - α-acetoxy ketones - iodine(III) catalysts - oxidation
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References
If the mixture was stirred at 40 °C for 4 h, it only needed to be cooled to r.t.